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食用混合了亚麻籽油、椰子油、葵花籽油和橄榄油的食用油,可显著改善高脂/高胆固醇饮食对斯普拉格-道利大鼠健康造成的负面影响。

Consumption of edible oil blended with flax, coconut, sunflower, and olive oil can significantly improve the negative health consequences of high-fat/high-cholesterol diet in Sprague Dawley rats.

作者信息

Rabail Roshina, Altemimi Ammar B, Maerescu Cristina Maria, Socol Claudia Terezia, Criste Florin Leontin, Khalid Abdur Rauf, Hussain Shahzad, Liu Zhi-Wei, Aadil Rana Muhammad

机构信息

National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan.

Department of Food Science, College of Agriculture, University of Basrah, Basrah, Iraq.

出版信息

Front Nutr. 2024 Sep 20;11:1469601. doi: 10.3389/fnut.2024.1469601. eCollection 2024.

DOI:10.3389/fnut.2024.1469601
PMID:39371945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11452909/
Abstract

BACKGROUND

Increasing cardiac, hepatic, and metabolic diseases have raised the need to modify our contemporary lifestyles toward balancing and diversifying the nutrients in our daily diet. Objective: Dietary fats should be modified to healthier versions by blending different vegetable oils. Therefore, in this study, an oil blend with health-protective and promoting fatty acid combinations was investigated to bring down the progression of cardiac and other metabolic diseases.

METHODOLOGY

A bio-efficacy trial was performed to investigate the therapeutic potential of an oil blend in 30 hyperlipidemic rats. Five rats were allocated to each group (coconut, flaxseed, olive, sunflower, and blended oil) for 42 days and were compared with the initial values of hyperlipidemic rats. Methodological investigations were performed for the body weight, naso-anal length, various obesity indices, visceral fat accumulation, blood and serum, cardiovascular risk indices, and echocardiograph.

RESULTS

Blended oil consumption indicated significant reductions of 53.12% in body fat content (3.98 ± 0.96), 6.82% in Lee index (289.60 ± 8.27), 16.84% in BMI (0.15 ± 0.003), 57.37% in total cholesterol (52.00 ± 9.03), 68.57% in triacylglycerides (99.00 ± 9.19), 61.16% in atherogenic index (0.88 ± 0.12), and 58.72% in coronary risk index (2.88 ± 0.12), when compared with the initial values.

CONCLUSION

Blended oil consumption has significantly reduced various obesity indices, improved lipid profile, and provided significant protection against cardiovascular risk indices. Moreover, the results of blended oil indicated significant health protective ameliorations in electrocardiographs. Its regular consumption could help to reduce the onset of obesity and metabolic diseases.

摘要

背景

心脏、肝脏和代谢性疾病日益增多,这就需要我们改变现代生活方式,使日常饮食中的营养成分更加均衡和多样化。目的:通过混合不同植物油,将膳食脂肪转变为更健康的形式。因此,在本研究中,对一种含有具有健康保护和促进作用的脂肪酸组合的混合油进行了研究,以减缓心脏和其他代谢性疾病的发展。

方法

进行了一项生物效能试验,以研究一种混合油对30只高脂血症大鼠的治疗潜力。将五只大鼠分配到每组(椰子油、亚麻籽油、橄榄油、葵花籽油和混合油),为期42天,并与高脂血症大鼠的初始值进行比较。对体重、鼻肛长度、各种肥胖指数、内脏脂肪堆积、血液和血清、心血管风险指数以及超声心动图进行了方法学研究。

结果

与初始值相比,食用混合油后,体脂含量显著降低了53.12%(3.98±0.96),李氏指数降低了6.82%(289.60±8.27),体重指数降低了16.84%(0.15±0.003),总胆固醇降低了57.37%(52.00±9.03),甘油三酯降低了68.57%(99.00±9.19),致动脉粥样硬化指数降低了61.16%(0.88±0.12),冠状动脉风险指数降低了58.72%(2.88±0.12)。

结论

食用混合油可显著降低各种肥胖指数,改善血脂状况,并为心血管风险指数提供显著保护。此外,混合油的结果表明在心电图方面有显著的健康保护改善作用。经常食用混合油有助于减少肥胖和代谢性疾病的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c69f/11452909/935ce1832e35/fnut-11-1469601-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c69f/11452909/935ce1832e35/fnut-11-1469601-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c69f/11452909/935ce1832e35/fnut-11-1469601-g001.jpg

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