精油与氯己定对致龋菌的比较
Comparison of Essential Oil with Chlorhexidine on Cariogenic Bacteria.
作者信息
Nazemisalman Bahareh, Seyede Solmaz Taheri MScD, Heydari Fatemeh, Yazdinezhad Alireza, Haghi Fakhri, Shabouei Jam Mahsa, Basir Shabestari Samira
机构信息
Dept. of Pediatric Dentistry, Dental School, Zanjan University of Medical Sciences, Zanjan, Iran.
Student Research Committee, Dept. of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
J Dent (Shiraz). 2024 Sep 1;25(3):223-228. doi: 10.30476/dentjods.2023.97602.2020. eCollection 2024 Sep.
STATEMENT OF THE PROBLEM
Dental caries and periodontal disease are the most common oral problems. Chemical antibacterial agents often have side effects; thus, researchers have long been in search for organic and herbal products to prevent dental caries and periodontal disease.
PURPOSE
The present study has aimed to assess the effects of essential oil on , , , and compared to Chlorhexidine (CHX).
MATERIALS AND METHOD
In this study, the plants were collected from Zanjan Province, Iran. Analysis of the essential oil was carried out by gas chromatography/mass chromatography. Micro-broth dilution and disc diffusion methods were used for assessment of the antimicrobial activity, and minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were evaluated.
RESULTS
The mean diameter of the growth inhibition zones in the well plate method for showed that it had greater antimicrobial activity against than others ( Value= 0.01). Furthermore, had higher antimicrobial activity than CHX. The results of MIC and MBC showed that had lower antibacterial activity than CHX.
CONCLUSION
essential oil demonstrated antibacterial properties against cariogenic bacteria. Given that other favorable properties of these essential oils are confirmed, they may be suitable for use as antibacterial agents in the formulation of oral healthcare products.
问题陈述
龋齿和牙周疾病是最常见的口腔问题。化学抗菌剂常常有副作用；因此，研究人员长期以来一直在寻找预防龋齿和牙周疾病的有机产品和草药产品。
目的
本研究旨在评估与氯己定（CHX）相比，精油对[此处原文缺失部分内容]、[此处原文缺失部分内容]、[此处原文缺失部分内容]和[此处原文缺失部分内容]的影响。
材料与方法
在本[此处原文缺失部分内容]研究中，植物采自伊朗赞詹省。通过气相色谱/质谱联用仪对精油进行分析。采用微量肉汤稀释法和纸片扩散法评估抗菌活性，并测定最低抑菌浓度（MIC）和最低杀菌浓度（MBC）。
结果
在平板法中，[此处原文缺失部分内容]的生长抑制圈平均直径表明，它对[此处原文缺失部分内容]的抗菌活性比其他物质更强（P值 = 0.01）。此外，[此处原文缺失部分内容]的抗菌活性高于CHX。MIC和MBC的结果表明，[此处原文缺失部分内容]的抗菌活性低于CHX。
结论
精油对致龋菌具有抗菌特性。鉴于这些精油的其他有利特性得到证实，它们可能适合用作口腔保健产品配方中的抗菌剂。
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