Antimicrobial Activity of Silver Nanoparticles Synthesized by the Green Method Using . Extract Against Oral Pathogenic Microorganisms.

Oral health is part of general health. Dental caries is the most common chronic disease worldwide. Considering the significance of plaque control, complications of chemical agents, and the optimal antimicrobial efficacy of nanoparticles, this study aimed to assess the antimicrobial activity of silver nanoparticles (AgNPs) synthesized by the green method using . extract against oral pathogenic microorganisms. In this in vitro experimental study, Rhus coriaria fruit was dried at room temperature. It was then ground, and its aqueous extract was obtained by the maceration technique. The effects of AgNPs synthesized by the green method in different concentrations were evaluated against (), (), (), (), and () using the well-plate technique. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values were also calculated. Data were analyzed by the Wilcoxon test, Kruskal-Wallis test, and Mann-Whitney test. The MIC values were 1024 µg/mL for and , and 512 µg/mL for , , and . The resistance of and was higher than that of , and . According to the growth inhibition zones and MBC test results, S. salivarius had the highest resistance to AgNPs followed by , , , and . AgNPs synthesized by the green method using extract was effective against oral pathogenic microorganisms. Thus, they may be used in the formulation of mouthwash and toothpaste.