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随机宇宙中的胚胎发育

Embryo Development in a Stochastic Universe.

作者信息

Elson Edward C

机构信息

Division of Neuropsychiatry, Microwave Bioeffects and Hazards Laboratory, Walter Reed Army Institute of Research, Bethesda, Maryland, USA.

出版信息

Bioelectricity. 2024 Sep 16;6(3):196-203. doi: 10.1089/bioe.2023.0050. eCollection 2024 Sep.

Abstract

Despite the elucidation of the many processes by which a single eukaryotic cell develops into a complex mature organism, it is still puzzling to some biologists how it is that an unvarying, interconnected set of processes becomes coordinated and insulated from a stochastic universe. This article suggests that electromagnetic processes deriving from the chemistry of an organism may provide such coordination. Specifically, the author develops the pacemaker concept, the periodic, autonomous electrical signal to the entire embryo, the result of which, after each pulse, is to alter or enlarge the transcriptome to produce the next level of complexity and maturity of the organism.

摘要

尽管已经阐明了单个真核细胞发育成复杂成熟生物体的许多过程,但对一些生物学家来说,一组不变且相互关联的过程如何变得协调并与随机的宇宙隔离开来,仍然令人困惑。本文认为,源自生物体化学过程的电磁过程可能提供这种协调。具体而言,作者提出了起搏器概念,即向整个胚胎发送周期性、自主性电信号,每次脉冲的结果是改变或扩大转录组,以产生生物体下一个层次的复杂性和成熟度。

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Embryo Development in a Stochastic Universe.随机宇宙中的胚胎发育
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Eliciting adverse effects data from participants in clinical trials.从临床试验参与者中获取不良反应数据。
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本文引用的文献

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Electromagnetic interactions in regulations of cell behaviors and morphogenesis.细胞行为和形态发生调控中的电磁相互作用。
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