Putranto Wachid, Pratama Yeremia Suryo, Krisandryka Krisandryka, Pangarso Eko Adi, Astuti Meira Dewi Kusuma, Prabowo Nurhasan Agung
Kidney and Hypertension Division, Department of Internal Medicine, Sebelas Maret University Hospital, Sukoharjo, Indonesia.
Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia.
Eur J Case Rep Intern Med. 2024 Sep 3;11(10):004850. doi: 10.12890/2024_004850. eCollection 2024.
The presentation of mineral bone disorder (MBD) in individuals with chronic kidney disease (CKD) may vary. Consequently, physicians should be capable of recognising this condition when there is a suspicion of its existence. This case report will describe a calcified maxilla tumour as a manifestation of CKD-MBD.
Initially asymptomatic, a 32-year-old female presented with progressive swelling of the upper left jaw. She had a history of routine haemodialysis. Further laboratory, radiological, and histopathological workup revealed the mass was indeed calcified maxillary fibroma arising from the manifestation of CKD-MBD.
This study underscores the significance of clinical comprehension of the broad-spectrum manifestations of CKD-MBD, including an initially asymptomatic mass. In addition, the screening of the patient's biochemical was required to determine the necessity of early intervention and improve the patient's outcome.
The case emphasises the importance of recognising atypical presentations of chronic kidney disease-mineral bone disorder (CKD-MBD), such as a calcified mass, which are rarely reported but critical for timely intervention.This report underscores the necessity for routine screening for secondary hyperparathyroidism in CKD patients, as early detection can significantly impact patient outcomes.Surgical management of the overlying mass and underlying parathyroid gland hyperplasia should always be considered in the management of the symptomatic CKD-MBD patient.
慢性肾脏病（CKD）患者的矿物质骨 disorder（MBD）表现可能各不相同。因此，医生在怀疑存在这种情况时应能够识别。本病例报告将描述一例作为CKD-MBD表现的钙化上颌骨肿瘤。
一名32岁女性最初无症状，随后出现左上颌渐进性肿胀。她有常规血液透析史。进一步的实验室、影像学和组织病理学检查显示，该肿块确实是由CKD-MBD表现引起的钙化上颌纤维瘤。
本研究强调了临床理解CKD-MBD广泛表现的重要性，包括最初无症状的肿块。此外，需要对患者进行生化检查，以确定早期干预的必要性并改善患者的预后。
该病例强调了识别慢性肾脏病-矿物质骨 disorder（CKD-MBD）非典型表现的重要性，如钙化肿块，这种情况很少报道，但对及时干预至关重要。本报告强调了对CKD患者常规筛查继发性甲状旁腺功能亢进的必要性，因为早期发现可显著影响患者预后。在有症状的CKD-MBD患者的管理中，应始终考虑对上颌肿块和潜在甲状旁腺增生进行手术治疗。
