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提高山羊卵母细胞存活率、生长率和成熟率的方法:巴西LAMOFOPA的主要成果

Approaches to improve survival, growth, and maturation of caprine oocytes: main results from LAMOFOPA-Brazil.

作者信息

de Figueiredo José Ricardo, da Silva Ana Flávia Bezerra, de Lima Laritza Ferreira

机构信息

Laboratório de Manipulação de Oócitos e Folículos Pré-antrais, Faculdade de Veterinária, Universidade Estadual do Ceará, Fortaleza, CE, Brasil.

出版信息

Anim Reprod. 2024 Sep 30;21(3):e20240059. doi: 10.1590/1984-3143-AR2024-0059. eCollection 2024.

Abstract

This brief review delves into the topic of follicle culture for embryo production, with a particular emphasis on goat models. Specifically, we examine the main findings from LAMOFOPA-Brazil over the last 20 years, highlighting the challenges posed by oxidative stress and epigenetic changes. Our focus is on strategies to improve follicular development and oocyte maturation. Furthermore, we underscore the valuable role of the antioxidant anethole in optimizing the efficacy of follicle culture and improving outcomes in embryo production.

摘要

本简要综述深入探讨了用于胚胎生产的卵泡培养这一主题,尤其侧重于山羊模型。具体而言,我们审视了巴西LAMOFOPA在过去20年的主要研究成果,强调了氧化应激和表观遗传变化所带来的挑战。我们的重点是改善卵泡发育和卵母细胞成熟的策略。此外,我们强调了抗氧化剂茴香脑在优化卵泡培养效果和改善胚胎生产结果方面的重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c0/11452086/8a0305aee12f/1984-3143-ar-21-3-e20240059-gf01.jpg

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