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妊娠期间漏诊的库欣综合征

Cushing's Syndrome Missed in Pregnancy.

作者信息

Sudarshanan Aditya, Koshy Rayna M, Mannath Sathia Narayanan, Fernandez Cornelius, Jacob Koshy

机构信息

Department of Acute Medicine, Pilgrim Hospital, United Lincolnshire Hospitals NHS Trust, Boston, GBR.

Department of Internal Medicine, New Cross Hospital, Royal Wolverhampton NHS Trust, Wolverhampton, GBR.

出版信息

Cureus. 2024 Oct 6;16(10):e70930. doi: 10.7759/cureus.70930. eCollection 2024 Oct.

DOI:10.7759/cureus.70930
PMID:39372381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11456285/
Abstract

Cushing's syndrome (CS) is uncommon during pregnancy and often difficult to diagnose due to similar symptoms shared with normal pregnancy. This case report discusses a 26-year-old woman who developed CS while pregnant, underlining the importance of early detection and the diagnostic challenges involved. The patient presented with gestational diabetes and pre-eclampsia during pregnancy. Post delivery, she continued to experience hypertension and facial swelling, which led to a diagnosis of CS. The patient underwent a successful laparoscopic adrenalectomy, which normalized her blood pressure and improved her symptoms. This case highlights the need for heightened awareness of CS in pregnant women exhibiting both gestational diabetes and hypertension, as early diagnosis and treatment are essential to reduce maternofoetal complications.

摘要

库欣综合征(CS)在孕期并不常见,且由于与正常妊娠有相似症状,常常难以诊断。本病例报告讨论了一名26岁女性在孕期患上CS的情况,强调了早期检测的重要性以及所涉及的诊断挑战。该患者在孕期出现妊娠糖尿病和子痫前期。产后,她持续出现高血压和面部肿胀,这导致了CS的诊断。患者接受了成功的腹腔镜肾上腺切除术,血压恢复正常,症状也有所改善。本病例凸显了对于同时患有妊娠糖尿病和高血压的孕妇,需要提高对CS的认识,因为早期诊断和治疗对于减少母婴并发症至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fad/11456285/6448062aab11/cureus-0016-00000070930-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fad/11456285/d8c2ed5084e0/cureus-0016-00000070930-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fad/11456285/6448062aab11/cureus-0016-00000070930-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fad/11456285/d8c2ed5084e0/cureus-0016-00000070930-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fad/11456285/6448062aab11/cureus-0016-00000070930-i02.jpg

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本文引用的文献

1
Diverse presentations of Cushing's syndrome during pregnancy - A case series.妊娠期间库欣综合征的多种表现形式——病例系列。
Aust N Z J Obstet Gynaecol. 2024 Aug;64(4):314-318. doi: 10.1111/ajo.13793. Epub 2024 Jan 29.
2
The diagnosis and management of Cushing's syndrome in pregnancy.妊娠合并库欣综合征的诊断与治疗。
J Neuroendocrinol. 2022 Aug;34(8):e13118. doi: 10.1111/jne.13118. Epub 2022 May 1.
3
Pregnancy during the course of Cushing's syndrome: a case report and literature review.库欣综合征病程中的妊娠:一例病例报告及文献综述
Endocrinol Diabetes Metab Case Rep. 2020 Apr 12;2020. doi: 10.1530/EDM-20-0022.
4
Pregnancy in Patients with Cushing's Syndrome.库欣综合征患者的妊娠问题。
Endocrinol Metab Clin North Am. 2018 Jun;47(2):441-449. doi: 10.1016/j.ecl.2018.02.004.
5
Cushing's syndrome and pregnancy outcomes: a systematic review of published cases.库欣综合征与妊娠结局:已发表病例的系统评价
Endocrine. 2017 Feb;55(2):555-563. doi: 10.1007/s12020-016-1117-0. Epub 2016 Oct 4.
6
Determination of nighttime salivary cortisol during pregnancy: comparison with values in non-pregnancy and Cushing's disease.孕期夜间唾液皮质醇的测定:与非孕期及库欣病的值进行比较。
Pituitary. 2016 Feb;19(1):30-8. doi: 10.1007/s11102-015-0680-3.
7
Late-night salivary cortisol for diagnosis of overt and subclinical Cushing's syndrome in hospitalized and ambulatory patients.夜间唾液皮质醇用于住院及门诊患者显性和亚临床库欣综合征的诊断
J Clin Endocrinol Metab. 2009 Feb;94(2):456-62. doi: 10.1210/jc.2008-1542. Epub 2008 Nov 11.
8
Cushing's syndrome during pregnancy: personal experience and review of the literature.妊娠期库欣综合征:个人经验及文献综述
J Clin Endocrinol Metab. 2005 May;90(5):3077-83. doi: 10.1210/jc.2004-2361. Epub 2005 Feb 10.
9
The effects of pregnancy on adrenal steroid metabolism.
Clin Sci. 1958 Feb;17(1):137-46.
10
Urocortin in pregnancy.孕期中的尿皮质素
Am J Obstet Gynecol. 1998 Aug;179(2):533-9. doi: 10.1016/s0002-9378(98)70391-6.