Ullah Sami, Noureddine Zahra, Sathian Brijesh, Narayanankutty Krishnaprasad, Asirvatham Thajus, Abubacker Muhaiadeen, Omar Moustafa, Awadh Mohammed Nassir, Al-Kuwari Fatima, Saad Rafat
Department of Physical Medicine and Rehabilitation, Qatar Rehabilitation Institute, Hamad Medical Corporation, Doha, Qatar.
MetroHealth Rehabilitation Institute of Ohio-Case Western Reserve University, Cleveland, OH, United States.
Qatar Med J. 2024 Sep 24;2024(3):45. doi: 10.5339/qmj.2024.45. eCollection 2024.
Patients recovering from severe COVID-19 infections have experienced prolonged cognitive, physical, and psychological sequelae, including cardiorespiratory and motor deconditioning, neurological deterioration, anxiety, and depression. The impact of rehabilitation post-acute COVID-19 infection was recognized in the literature, but studies assessing and quantifying specific functional outcomes were lacking. This study aims to describe the characteristics and quantify the changes in functional outcomes of patients admitted to Qatar Rehabilitation Institute (QRI) for inpatient rehabilitation (IPR) post-COVID-19 infection during a 10-month period in 2021.
This is a retrospective observational cohort study, which included individuals over 18 years of age with a documented COVID-19-positive diagnosis who were admitted to QRI for IPR due to COVID-19 complications. Data was collected by the investigators from January 1, 2021, until October 30, 2021. A total of 243 patients were included in this study. The changes in functional rehabilitation outcomes were assessed and quantified at both the patient's baseline (on admission to QRI) and after completion of IPR (on discharge). The duration of the IPR program varied based on each patient's baseline assessment. Patients were given a total of 8-12 weeks to achieve their rehabilitation goals and were discharged once those goals were met. Several validated tools were utilized in this study including Functional Independence Measure (FIM), Berg Balance Scale (BBS), Dynamic Gait Index (DGI), Modified Medical Research Council (mMRC) Dyspnea Scale, Mini-Mental State Examination (MMSE), and Right- and left-Hand Grip Strength. In addition, patients' diet, the need for respiratory support, and the presence of a tracheostomy tube before and after IPR were also recorded.
In total, 84.4% of the included patients were males (n = 205); with a mean age of 52.44 ± 12.99 years. The most commonly reported comorbidities were type 2 diabetes (62.1%) and hypertension (49.8%) with 83.5% of patients experiencing critical illness neuromyopathy. The average patients' length of stay in QRI was 33.92 ± 27.72 days. A statistically significant improvement in all functional outcome scales was noted following the completion of the IPR program ( = 0.001). The number of patients requiring modification to their diet or feeding via nasogastric tube (NGT) significantly decreased by 35% and 93%, respectively ( = 0.001). Patients requiring respiratory support decreased by 98% ( = 0.001) and the need for a tracheostomy tube among patients was reduced by 95% ( = 0.001).
IPR following COVID-19 infection was associated with significant functional, motor, and cardiorespiratory improvement. Dedicating clinics for post-COVID-19 rehabilitation would ensure improved patient outcomes and enhanced recovery.
从重症 COVID-19 感染中康复的患者经历了长期的认知、身体和心理后遗症,包括心肺功能和运动功能减退、神经功能恶化、焦虑和抑郁。急性 COVID-19 感染后康复的影响在文献中已得到认可,但缺乏评估和量化特定功能结局的研究。本研究旨在描述 2021 年 10 个月期间因 COVID-19 感染后并发症入住卡塔尔康复研究所(QRI)进行住院康复(IPR)的患者的特征,并量化其功能结局的变化。
这是一项回顾性观察队列研究,纳入了 18 岁以上有 COVID-19 阳性诊断记录且因 COVID-19 并发症入住 QRI 进行 IPR 的个体。研究人员于 2021 年 1 月 1 日至 2021 年 10 月 30 日收集数据。本研究共纳入 243 名患者。在患者基线(入住 QRI 时)和 IPR 完成后(出院时)评估并量化功能康复结局的变化。IPR 项目的持续时间根据每位患者的基线评估而有所不同。患者共有 8 - 12 周的时间来实现其康复目标,一旦达到这些目标即可出院。本研究使用了几种经过验证的工具,包括功能独立性测量(FIM)、伯格平衡量表(BBS)、动态步态指数(DGI)、改良医学研究委员会(mMRC)呼吸困难量表、简易精神状态检查表(MMSE)以及左右手握力。此外,还记录了患者的饮食情况、呼吸支持需求以及 IPR 前后气管造口管的使用情况。
总共,纳入患者中的 84.4%为男性(n = 205);平均年龄为 52.44 ± 12.99 岁。最常见的合并症是 2 型糖尿病(62.1%)和高血压(49.8%),83.5%的患者患有危重病性神经病变。患者在 QRI 的平均住院时间为 33.92 ± 27.72 天。IPR 项目完成后,所有功能结局量表均有统计学意义上的显著改善(P = 0.001)。需要调整饮食或通过鼻胃管(NGT)喂食的患者数量分别显著减少了 35%和 93%(P = 0.001)。需要呼吸支持的患者减少了 98%(P = 0.001),患者中气管造口管的需求减少了 95%(P = 0.001)。
COVID-19 感染后的 IPR 与功能、运动和心肺功能的显著改善相关。设立 COVID-19 后康复诊所将确保改善患者结局并促进康复。