Jamieson S W
West J Med. 1985 Dec;143(6):829-33.
Combined heart-lung transplantation has now been carried out in 27 patients at Stanford University Medical Center. All recipients had suffered from pulmonary hypertension, either primary or the result of Eisenmenger's syndrome. The one-year survival has been approximately 70%. All survivors returned to normal activity, though later respiratory difficulty has been encountered in some of these patients and has required retransplantation in one. These late occurrences are likely the result of inadequate control of rejection. Heart and lung transplantation has been shown to be an effective therapy for otherwise progressively fatal pulmonary conditions, and, in the case of Eisenmenger's syndrome, has presented a therapeutic avenue for the first time. The late complications encountered in some of these patients can probably be averted with increased experience.
斯坦福大学医学中心现已对27名患者实施了心肺联合移植手术。所有接受者均患有肺动脉高压，病因要么是原发性的，要么是艾森曼格综合征所致。一年生存率约为70%。所有存活者都恢复了正常活动，不过其中一些患者后来出现了呼吸困难，有一例还需要再次移植。这些后期出现的情况可能是排斥反应控制不当的结果。心肺移植已被证明是治疗其他方面会逐渐致命的肺部疾病的有效疗法，而且对于艾森曼格综合征而言，首次提供了一种治疗途径。随着经验的增加，这些患者中部分人所遇到的后期并发症或许可以避免。
