Huang Huishi, Liu Linru, You Cong, Chen Kaiyun, Xing Yu, Li Yijie, Deng Hongzhu
Child Development and Behavior Center, Third Affiliated Hospital of Sun Yat-sen University, No.600, Tianhe Road, Tianhe District, Guangzhou, Guangdong Province, China.
J Autism Dev Disord. 2024 Oct 7. doi: 10.1007/s10803-024-06575-0.
The purpose of this study was to validate the utility of the Systematic Observation of Red Flags (SORF) for autism screening during 10-minute parent-child interactions at ages 15-24 months. A total of 54 children participated in this study, including 19 with autism spectrum disorder (ASD), 23 with developmental delay, and 12 typically developing children. Coders coded 10-minute videos of parent-child interactions based on the defined scoring criteria. The discriminative ability for outcome diagnosis was evaluated for total score, social communication score, restricted repetitive behavior score, number of red flags, and composite score. SORF scores demonstrated good discriminative ability between ASD and non-ASD children, with the composite score (AUC = 0.884) showing the best discriminative ability for outcome diagnosis and predicting likelihood of ASD in young children. The composite score represented a simplified measurement, with the cutoff score of 7 and sensitivity and specificity of 0.789 and 0.800, respectively.
本研究的目的是验证在15至24个月龄儿童10分钟的亲子互动中，红旗系统观察法（SORF）用于自闭症筛查的效用。共有54名儿童参与了本研究，其中19名患有自闭症谱系障碍（ASD），23名有发育迟缓，12名发育正常。编码人员根据既定的评分标准对10分钟的亲子互动视频进行编码。对总分、社交沟通得分、受限重复行为得分、红旗数量和综合得分评估结果诊断的判别能力。SORF得分显示出ASD儿童与非ASD儿童之间具有良好的判别能力，综合得分（AUC = 0.884）对结果诊断和预测幼儿患ASD的可能性显示出最佳判别能力。综合得分代表一种简化测量方法，临界值为7，灵敏度和特异度分别为0.789和0.800。
