Kuzemenská P, Komínková B, Mackŭ M, Duniewicz M, Jezek P, Stanková M
J Hyg Epidemiol Microbiol Immunol. 1982;26(1):57-64.
The Slidex-méningite-Kit allows the used of the rather highly sensitive and specific latex-agglutination method for the detection of N. meningitis group A and C and H. influenzae b exoantigens within a few minutes. In model experiments positive results persisted at unchanged intensity for prolonged periods of time regardless of storage temperature. However, in practical trials performed in a set of 60 spinal fluids from purulent meningitis patients etiological agent identification by the slidex-méningite-Kit failed at least as frequently as by cultivation; in the case of meningococci the kit even failed more often than cultivation. Hence the Slidex-méningite-Kit should be regarded as an auxiliary tool in the diagnosis of purulent meningitis and one that cannot replace the classical methods of cultivation and preparation staining. In the case of positive results, advantages of the Slides-méingite-Kit are rapidity in etiological agent identification and prolonged persistence of positivity in the spinal fluid samples.
Slidex脑膜炎试剂盒可在几分钟内使用灵敏度和特异性都相当高的乳胶凝集法检测A群和C群脑膜炎奈瑟菌以及b型流感嗜血杆菌的外毒素。在模型实验中，无论储存温度如何，阳性结果在很长一段时间内强度都保持不变。然而，在对60例化脓性脑膜炎患者的脑脊液进行的实际试验中，Slidex脑膜炎试剂盒进行病原体鉴定时失败的频率至少与培养法相同；对于脑膜炎球菌，该试剂盒失败的频率甚至比培养法更高。因此，Slidex脑膜炎试剂盒应被视为化脓性脑膜炎诊断中的一种辅助工具，而不能替代传统的培养和制备染色方法。如果结果呈阳性，Slidex脑膜炎试剂盒的优点是病原体鉴定迅速，且脑脊液样本中的阳性结果持续时间长。
