Department of Vascular Surgery, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 2, FI-00290 Helsinki, Finland.
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Eur Heart J. 2024 Nov 21;45(44):4747-4757. doi: 10.1093/eurheartj/ehae665.
In 2006, screening of 65-year-old men for abdominal aortic aneurysm (AAA) was started in Sweden. Decline in aneurysm-related mortality has been reported since, but aneurysm incidence has been diminishing globally. Neighbouring Finland with similar population structure and health care system has no AAA screening programme. The aim of this study was to compare incidence and results of AAA repair in Sweden and Finland to differentiate the effect of screening from other changes in the epidemiology and treatment of AAA.
All repairs for intact AAA (iAAA) or ruptured AAA (rAAA) from 1998 to 2017 were identified from national registers, and mortality data for these patients were collected.
A total of 15 927 operations for iAAA were performed in Sweden and 6933 in Finland. In Sweden, the yearly operation volume increased after introduction of screening. Both countries showed a decrease in number of rAAA operations, but the decrease was more pronounced in Sweden. Sweden had a higher proportion of all AAA repairs because of rupture in the start of the study but by the end, the proportions were similar in both countries. Long-term survival improved for 65-79-old men in Sweden after start of screening.
This study reveals improvements in results of AAA repair in Sweden. A decrease in rAAA repair and increase in iAAA repair were evident after AAA screening was started in 2006 and resulted in better outcomes. These changes are likely the result of AAA screening as they cannot be seen in neighbouring Finland that is lacking an AAA screening programme.
2006 年,瑞典开始对 65 岁男性进行腹主动脉瘤(AAA)筛查。自那时起,AAA 相关死亡率呈下降趋势,但全球范围内的 AAA 发病率一直在下降。与瑞典具有相似人口结构和医疗保健系统的邻国芬兰没有 AAA 筛查计划。本研究旨在比较瑞典和芬兰的 AAA 发病率和修复结果,以区分筛查的效果与 AAA 流行病学和治疗的其他变化。
从国家登记处确定了 1998 年至 2017 年所有未破裂 AAA(iAAA)或破裂 AAA(rAAA)的修复,并收集了这些患者的死亡率数据。
瑞典共进行了 15927 例 iAAA 手术,芬兰进行了 6933 例。在瑞典,引入筛查后,每年的手术量增加。两国的 rAAA 手术数量均有所减少,但瑞典的减少幅度更大。由于研究开始时瑞典破裂的 AAA 占所有 AAA 修复的比例较高,但到研究结束时,两国的比例相似。瑞典 65-79 岁男性的长期生存率在开始筛查后有所提高。
本研究揭示了瑞典 AAA 修复结果的改善。自 2006 年开始 AAA 筛查以来,rAAA 修复减少和 iAAA 修复增加明显,导致更好的结果。这些变化很可能是 AAA 筛查的结果,因为在没有 AAA 筛查计划的邻国芬兰并没有看到这些变化。