Greve Katarina, Ek Stina, Bartha Erzsébet, Modig Karin, Hedström Margareta
Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Function Perioperative Medicine and Intensive Care (PMI), Karolinska University Hospital, Stockholm, Sweden.
Bone Jt Open. 2024 Oct 8;5(10):843-850. doi: 10.1302/2633-1462.510.BJO-2024-0028.R1.
The primary aim of this study was to compare surgical methods (sliding hip screw (SHS) vs intramedullary nailing (IMN)) for trochanteric hip fracture in relation to death within 120 days after surgery and return to independent living. The secondary aim was to assess whether the associations between surgical method and death or ability to return to independent living varied depending on fracture subtype or other patient characteristics.
A total of 27,530 individuals from the Swedish Hip Fracture Register RIKSHÖFT (SHR) aged ≥ 70 years, admitted to hospital between 1 January 2014 and 31 December 2019 with trochanteric hip fracture, were included. Within this cohort, 12,041 individuals lived independently at baseline, had follow-up information in the SHR, and were thus investigated for return to independent living. Death within 120 days after surgery was analyzed using Cox regression with SHS as reference and adjusted for age and fracture type. Return to independent living was analyzed using logistic regression adjusted for age and fracture type. Analyses were repeated after stratification by fracture type, age, and sex.
Overall, 2,171 patients (18%) who were operated with SHS and 2,704 patients (18%) who were operated with IMN died within 120 days after surgery. Adjusted Cox regression revealed no difference in death within 120 days for the whole group (hazard ratio 0.97 (95% CI 0.91 to 1.03)), nor after stratification by fracture type. In total, 3,714 (66%) patients who were operated with SHS and 4,147 (64%) patients who were operated with IMN had returned to independent living at follow-up. There was no significant difference in return to independent living for the whole group (odds ratio 0.95 (95% CI 0.87 to 1.03)), nor after stratification by fracture type.
No overall difference was observed in death within 120 days or return to independent living following surgery for trochanteric hip fracture, depending on surgical method (SHS vs IMN) in this recent Swedish cohort, but there was a suggested benefit for SHS in subgroups of patients.
本研究的主要目的是比较手术方法(滑动髋螺钉(SHS)与髓内钉固定(IMN))治疗转子间髋部骨折后120天内的死亡率及恢复独立生活的情况。次要目的是评估手术方法与死亡或恢复独立生活能力之间的关联是否因骨折亚型或其他患者特征而异。
纳入瑞典髋部骨折登记处RIKSHÖFT(SHR)中2014年1月1日至2019年12月31日期间因转子间髋部骨折入院的27530名年龄≥70岁的个体。在该队列中,12041名个体在基线时独立生活,在SHR中有随访信息,因此对其恢复独立生活的情况进行了调查。采用以SHS为对照的Cox回归分析手术120天内的死亡情况,并对年龄和骨折类型进行校正。采用对年龄和骨折类型校正的逻辑回归分析恢复独立生活的情况。按骨折类型、年龄和性别分层后重复分析。
总体而言,2171例(18%)接受SHS手术的患者和2704例(18%)接受IMN手术的患者在术后120天内死亡。校正后的Cox回归显示,整个组在120天内的死亡率无差异(风险比0.97(95%CI 0.91至1.03)),按骨折类型分层后也无差异。总共3714例(66%)接受SHS手术的患者和4147例(64%)接受IMN手术的患者在随访时恢复了独立生活。整个组在恢复独立生活方面无显著差异(优势比0.95(95%CI 0.87至1.03)),按骨折类型分层后也无差异。
在这个近期的瑞典队列中,对于转子间髋部骨折患者,术后120天内的死亡率或恢复独立生活的情况,根据手术方法(SHS与IMN)未观察到总体差异,但在部分亚组患者中SHS显示出一定益处。