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髓内钉治疗转子间骨折的死亡率增加:19935 例患者中滑动髋螺钉与髓内钉的比较。

Increased mortality after intramedullary nailing of trochanteric fractures: a comparison of sliding hip screws with nails in 19,935 patients.

机构信息

Department of Surgical Sciences, Orthopaedics, Uppsala University, Uppsala.

Department of Surgical and Perioperative Sciences at Umeå University, Umeå.

出版信息

Acta Orthop. 2022 Jan 3;93:146-150. doi: 10.2340/17453674.2021.862.

Abstract

Background and purpose - Intramedullary nails (IMN) have become increasingly common as treatment for trochanteric hip fractures (THF) although they are costlier, and without proven superiority compared with sliding hip screws (SHS). We investigated whether the 2 methods differ in terms of short-term mortality when used in fractures where both methods are suitable. Patients and methods - We extracted data from the Swedish Fracture Register (SFR) on 19,935 patients ≥ 60 years with trochanteric fractures AO type 31-A1 or -A2 who had been treated with either SHS or IMN. We assessed absolute mortality rates and the relative risks (RR) of death after 7, 30, 90, and 365 days using generalized linear models, adjusting for age, sex, and fracture type. We performed a sensitivity analysis on a subgroup of 3,673 patients with information on comorbidity to address this potential confounder. Results - 69% of the patients were women and mean age was 84 years (60-107). IMN was used in 35% of A1 and in 71% of A2 fractures. The use of IMN was associated with a slightly increased adjusted risk of death within 30 days compared with SHS (RR = 1.1, 95% CI 1.0-1.2) with no difference at any other time point. Interpretation - The slightly increased risk of death up to 30 days postoperatively does not support the use of IMN instead of SHS in stable THF.

摘要

背景与目的-髓内钉(IMN)已成为治疗转子间髋部骨折(THF)的常用方法,尽管其成本更高,且与滑动髋螺钉(SHS)相比并无明显优势。我们研究了在两种方法均适用的情况下,这两种方法在短期死亡率方面是否存在差异。

患者和方法-我们从瑞典骨折登记处(SFR)中提取了 19935 名年龄≥60 岁、AO 31-A1 或-A2 型转子间骨折、接受 SHS 或 IMN 治疗的患者数据。我们使用广义线性模型评估了 7、30、90 和 365 天后的绝对死亡率和死亡相对风险(RR),并对年龄、性别和骨折类型进行了调整。我们对 3673 名有合并症信息的患者进行了敏感性分析,以解决这一潜在混杂因素。

结果-69%的患者为女性,平均年龄为 84 岁(60-107 岁)。31-A1 型骨折中 IMN 的使用率为 35%,31-A2 型骨折中 IMN 的使用率为 71%。与 SHS 相比,IMN 在 30 天内调整后的死亡风险略有增加(RR=1.1,95%CI 1.0-1.2),在其他任何时间点均无差异。

解释-术后 30 天内死亡风险略有增加,不支持在稳定的 THF 中使用 IMN 代替 SHS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94e5/8815803/b6a7335ca939/ActaO-93-862-g001.jpg

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