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孕期抗抑郁药使用决策:对英国部分女性样本的定性访谈研究

Making decisions about antidepressant use during pregnancy: a qualitative interview study of a sample of women in the UK.

作者信息

James Heather, Smith Sophie, Rai Dheeraj, Culpin Iryna, Turner Katrina

机构信息

Centre for Academic Mental Health, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol.

Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London, London; honorary research fellow, Centre for Academic Mental Health, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol.

出版信息

Br J Gen Pract. 2025 May 29;75(755):e440-e447. doi: 10.3399/BJGP.2024.0068. Print 2025 Jun.

Abstract

BACKGROUND

An increasing number of pregnant women now take antidepressants. Many pregnant women experience decisional conflict when deciding whether to take antidepressants, but little is known about the attitudes and experiences that influence these decisions.

AIM

To explore the attitudes and experiences influencing women's decisions about antenatal antidepressant use.

DESIGN AND SETTING

A qualitative study using in-depth interviews with a sample of UK women who experienced antenatal depression or took antidepressants antenatally within the preceding 3 years.

METHOD

Recruitment adverts were placed by a perinatal mental health charity and on parenting forums and social media platforms, resulting in a convenience sample. Interview data were coded and analysed with thematic analysis using QSR NVivo.

RESULTS

Twenty-two women were interviewed; one-half had taken antidepressants during pregnancy. Most women had concerns about adverse effects and viewed antidepressants as adjunctive to non-pharmacological treatments, which were reported as difficult to access. Some women reported that professional advice was insufficiently detailed. Women described the need to cope with their symptoms, their baby, and existing responsibilities, and related their decisions to their perceived ability to cope. This perception was influenced by physical and emotional challenges relating to pregnancy. Women's decisions were influenced by their previous experiences and by the perceived societal expectations placed on pregnant women.

CONCLUSION

Decision making is a complex and dynamic process, personal to each woman's circumstances. Perceived ability to cope is an important factor in decision making. Detailed information should be offered to women for support with decision making in relation to antenatal medication use.

摘要

背景

现在越来越多的孕妇服用抗抑郁药。许多孕妇在决定是否服用抗抑郁药时会经历决策冲突,但对于影响这些决策的态度和经历却知之甚少。

目的

探讨影响女性关于产前使用抗抑郁药决策的态度和经历。

设计与背景

一项定性研究,对英国在过去3年内经历过产前抑郁或产前服用过抗抑郁药的女性样本进行深入访谈。

方法

由围产期心理健康慈善机构以及在育儿论坛和社交媒体平台上发布招募广告,从而获得一个便利样本。使用QSR NVivo软件,通过主题分析对访谈数据进行编码和分析。

结果

对22名女性进行了访谈;其中一半在孕期服用过抗抑郁药。大多数女性担心药物的不良反应,并将抗抑郁药视为非药物治疗的辅助手段,她们表示难以获得非药物治疗。一些女性报告称专业建议不够详细。女性们描述了应对自身症状、照顾宝宝以及履行现有责任的需求,并将她们做出的决策与自己感知到的应对能力联系起来。这种感知受到与怀孕相关的身体和情绪挑战的影响。女性的决策受到她们以往经历以及她们所感知到的社会对孕妇期望的影响。

结论

决策是一个复杂且动态的过程,因每位女性的具体情况而异。感知到的应对能力是决策中的一个重要因素。应该为女性提供详细信息,以支持她们在产前用药方面的决策。

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Prevalence and correlates of perinatal depression.围产期抑郁的流行情况及其相关因素。
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