Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, No. 420, Fuma Road, Jinan District, Fuzhou, 350014, China.
Fujian Key Laboratory of Advanced Technology for Cancer Screening and Early Diagnosis, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.
Sci Rep. 2024 Oct 7;14(1):23273. doi: 10.1038/s41598-024-74581-4.
The study aimed to assess the prospective associations between sleep duration, sleep restfulness, midday napping and hip fracture (HF) and falls in a nationally representative Chinese population. Data were from the China Health and Retirement Longitudinal Study which was conducted from 2013 to 2018. In total, 10,508 individuals without a history of HF in 2013 were included. Nighttime sleep duration, sleep restfulness and midday napping were self-reported. Logistic regression analyses were performed to examine the relationships between sleep problems and HF as well as falls, adjusting for covariates. A total of 313 (3.0%) participants reported HF, and 3899 (37.1%) experienced at least one fall event over the following 5-year period. Participants who had a short sleep duration (≤ 6) were more likely to report HF (OR = 1.27, 95% CI = 1.00-1.62) and falls (OR = 1.18, 95% CI = 1.07-1.30) than those who had a normal sleep duration (6-9 h) in the fully adjusted model. Participants having unrestful sleep were also more likely to report falls (OR = 1.23, 95% CI = 1.11-1.36) than those who had restful sleep. However, there was no significant association between midday napping and HF and falls. In conclusion, short sleep duration and sleep restfulness were independently associated with an increased risk of HF and falls, which may have important clinical and public health implications. Interventions to improve sleep quality may reduce the risk of HF and fall accidents among middle-aged and older people.
本研究旨在评估中国代表性人群中睡眠时长、睡眠质量、午睡与髋部骨折(HF)和跌倒之间的前瞻性关联。数据来自于 2013 年至 2018 年开展的中国健康与养老追踪调查。共有 10508 名 2013 年无 HF 病史的个体纳入研究。夜间睡眠时长、睡眠质量和午睡均通过自我报告获得。采用 logistic 回归分析调整协变量后,考察了睡眠问题与 HF 和跌倒之间的关系。共有 313 名(3.0%)参与者报告了 HF,3899 名(37.1%)参与者在随后的 5 年期间至少发生了 1 次跌倒事件。与睡眠正常(6-9 小时)的参与者相比,睡眠时间较短(≤6 小时)的参与者更有可能报告 HF(OR=1.27,95%CI=1.00-1.62)和跌倒(OR=1.18,95%CI=1.07-1.30),在完全调整模型中。睡眠质量差的参与者也更有可能报告跌倒(OR=1.23,95%CI=1.11-1.36)。然而,午睡与 HF 和跌倒之间并无显著关联。总之,短睡眠时长和睡眠质量差与 HF 和跌倒风险增加独立相关,这可能具有重要的临床和公共卫生意义。改善睡眠质量的干预措施可能会降低中老年人群 HF 和跌倒事故的风险。