Ragheb Ahmed M, Lotfy Amr M, Fahmy Mohamed, Elmarakbi Akrm A
Department of Urology, Faculty of Medicine, Beni‑Suef University, Beni‑Suef, Egypt.
Basic Clin Androl. 2024 Oct 8;34(1):16. doi: 10.1186/s12610-024-00232-3.
Affected sexual relationships affect both the quality of life of men and women. Platelet-derived therapies are becoming increasingly popular in various medical and surgical fields because of their ability to aid in tissue healing and vascular remodeling. This study aimed to assess the safety and effectiveness of platelet-rich plasma (PRP) injections in treating patients with erectile dysfunction (ED).
Fifty-two participants with mild to moderate ED were divided into two groups: group A, who received three PRP penile injections, and group B, who received three saline injections (5 ml for each injection site). The International Index of Erectile Function (IIEF) was used to evaluate all participants. A month after the last injection, the PRP group's IIEF was 16.12 ± 1.25, while the placebo group's was 15.99 ± 1.21 (p = 0.683). Following a 3-month period, the IIEF for the PRP group was 16.44 ± 1.17, while the placebo group's was 16.31 ± 1.06 (p value = 0.653). Following a 6-month period, the IIEF for the PRP group was 16.35 ± 1.45, while that for the placebo group's was 16.23 ± 1.19 (p = 0.727). In terms of IIEF, there was no significant difference between the two groups after one, three, and six months of treatment.
In brief, our research revealed no data to support the application of PRP injections in the management of mild-to-moderate ED.
受影响的性关系会影响男性和女性的生活质量。血小板衍生疗法因其有助于组织愈合和血管重塑的能力，在各种医学和外科领域越来越受欢迎。本研究旨在评估富血小板血浆（PRP）注射治疗勃起功能障碍（ED）患者的安全性和有效性。
52名轻度至中度ED患者被分为两组：A组接受3次PRP阴茎注射，B组接受3次盐水注射（每个注射部位5毫升）。使用国际勃起功能指数（IIEF）对所有参与者进行评估。最后一次注射后一个月，PRP组的IIEF为16.12±1.25，而安慰剂组为15.99±1.21（p = 0.683）。3个月后，PRP组的IIEF为16.44±1.17，而安慰剂组为16.31±1.06（p值 = 0.653）。6个月后，PRP组的IIEF为16.35±1.45，而安慰剂组为16.23±1.19（p = 0.727）。在IIEF方面，两组在治疗1个月、3个月和6个月后没有显著差异。
简而言之，我们的研究没有发现数据支持PRP注射用于治疗轻度至中度ED。
