Department of Public Health, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, 8F-8068, No. 138, ShengLi Rd., North Dist., Tainan City, 704, Taiwan.
Institute of Health Behaviors and Community Sciences, College of Public Health, National Taiwan University, Taipei, Taiwan.
Harm Reduct J. 2024 Oct 7;21(1):181. doi: 10.1186/s12954-024-01094-8.
Polydrug use in the context of chemsex is commonplace among gay, bisexual, and other men-who-have-sex-with-men (GBMSM). This study aimed to examine the differences in experiences of physical, social, and psychological harms, as well as mental ill-health among GBMSM who use different combinations of methamphetamine and gamma-hydroxybutyric acid/gamma-butyrolactone (GHB/GBL) during chemsex.
Adult GBMSM participants who had experience of chemsex in the past 12 months participated in a cross-sectional online survey in Taiwan and self-reported their sociodemographic background, sexual behaviours, mental health, and experiences of harm following a chemsex session. We used univariable and multivariable logistic regression to assess the different experiences of harm and mental ill-health among GBMSM who engaged in chemsex without using methamphetamine, used methamphetamine but not GHB/GBL, and who used both drugs.
Out of 510 participants who completed all items included in the analysis, 24.1% engaged in chemsex without using methamphetamine, 36.9% used methamphetamine but not GHB/GBL, and 39.0% used both drugs. Eighty five percent of men who used both methamphetamine and GHB/GBL reported at least one kind of social harm after a chemsex session, such as missing dates or appointments, or appearing "high" at work, followed by used methamphetamine but not GHB/GBL (69.7%) and those without using methamphetamine (37.4%). After controlling for polydrug and frequency of drug use in the multivariable logistic regression, those who used methamphetamine but not GHB/GBL and those who used both drugs were more likely to report experiencing physical and psychological harms compared to those who did not use methamphetamine (p < 0.003).
GBMSM who used both methamphetamine and GHB/GBL in a chemsex context were more likely to report experience of harms than those who only used a single chemsex drug or engaged in chemsex without methamphetamine or GHB/GBL. Harm reduction should focus on both preventing HIV and STI transmission and on minimising psychosocial harm to GBMSM, with varying impacts depending on drug use.
在男同性恋、双性恋和其他与男性发生性关系的男性(GBMSM)中,化学性行为背景下的多药使用很常见。本研究旨在探讨在化学性行为中使用不同组合的甲基苯丙胺和γ-羟基丁酸/γ-丁内酯(GHB/GBL)的 GBMSM 之间,身体、社会和心理伤害以及心理健康不良经历的差异。
过去 12 个月内有过化学性行为经历的成年 GBMSM 参与者参加了台湾的一项横断面在线调查,并在化学性行为后自我报告了他们的社会人口背景、性行为、心理健康和伤害经历。我们使用单变量和多变量逻辑回归来评估在化学性行为中不使用甲基苯丙胺、使用甲基苯丙胺但不使用 GHB/GBL 以及同时使用两种药物的 GBMSM 之间不同的伤害和心理健康不良经历。
在完成分析中包括的所有项目的 510 名参与者中,24.1%的人没有使用甲基苯丙胺进行化学性行为,36.9%的人使用甲基苯丙胺但不使用 GHB/GBL,39.0%的人同时使用两种药物。85%同时使用甲基苯丙胺和 GHB/GBL 的男性在化学性行为后报告了至少一种社会伤害,例如错过约会或预约,或在工作中表现得“兴奋”,其次是使用甲基苯丙胺但不使用 GHB/GBL(69.7%)和不使用甲基苯丙胺的人(37.4%)。在多变量逻辑回归中控制多药和药物使用频率后,与不使用甲基苯丙胺的人相比,使用甲基苯丙胺但不使用 GHB/GBL 的人和同时使用两种药物的人更有可能报告身体和心理伤害(p<0.003)。
在化学性行为背景下同时使用甲基苯丙胺和 GHB/GBL 的 GBMSM 比仅使用单一化学性行为药物或不使用甲基苯丙胺或 GHB/GBL 进行化学性行为的人更有可能报告伤害经历。减少伤害应该既侧重于预防 HIV 和性传播感染的传播,又侧重于最大限度地减少对 GBMSM 的心理社会伤害,具体影响取决于药物使用情况。