Department of Public Health, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Popul Health Metr. 2024 Oct 7;22(1):26. doi: 10.1186/s12963-024-00342-0.
The aims of this study were to establish national disability weights based on the health state preferences of a Dutch general population sample, examine the relation between results and respondent's characteristics, and compare disability weights with those estimated in the European disability weights study.
In this cross-sectional study, a web-based survey was administered to a general population 18-75 years from the Netherlands. The survey included paired comparison questions. Paired comparison data were analysed using probit regression and located results onto the 0-to-1 disability weight scale using non-parametric regression. Bootstrapping was used to estimate 95% uncertainty intervals (95%UI). Spearman's correlation was used to investigate the relation of probit regression coefficients between respondent's characteristics.
3994 respondents completed the questionnaire. The disability weights ranged from 0.007 (95%UI: 0.003-0.012) for mild distance vision impairment to 0.741 (95% UI: 0.498-0.924) for intensive care unit admission. Spearman's correlation of probit coefficients between sub-groups based on respondent's characteristics were all above 0.95 (p < 0.001). Comparison of disability weights of 140 health states that were included in the Dutch and European disability weights study showed a high correlation (Spearman's correlation: 0.942; p < 0.001); however, for 76 (54.3%) health states the point estimate of the Dutch disability weight fell outside of the 95%UI of the European disability weights.
Respondent's characteristics had no influence on health state valuations with the paired comparison. However, comparison of the Dutch disability weights to the European disability weights indicates that health state preferences of the general population of the Netherlands differ from those of other European countries.
本研究旨在基于荷兰一般人群样本的健康状况偏好建立全国残疾权重,检验结果与应答者特征之间的关系,并与欧洲残疾权重研究中估计的残疾权重进行比较。
在这项横断面研究中,我们向荷兰 18-75 岁的一般人群进行了一项基于网络的调查。该调查包括配对比较问题。使用概率回归分析配对比较数据,并使用非参数回归将结果定位到 0 到 1 的残疾权重标度上。采用自举法估计 95%置信区间(95%CI)。采用 Spearman 相关系数来检验应答者特征之间概率回归系数的关系。
3994 名应答者完成了问卷。残疾权重范围从轻度远视力障碍的 0.007(95%CI:0.003-0.012)到重症监护病房入院的 0.741(95%CI:0.498-0.924)。基于应答者特征的亚组之间概率系数的 Spearman 相关系数均高于 0.95(p<0.001)。将荷兰和欧洲残疾权重研究中纳入的 140 种健康状况的残疾权重进行比较,显示出高度相关性(Spearman 相关系数:0.942;p<0.001);然而,对于 76 种(54.3%)健康状况,荷兰残疾权重的点估计值落在欧洲残疾权重的 95%CI 之外。
配对比较中应答者特征对健康状况评估没有影响。然而,将荷兰残疾权重与欧洲残疾权重进行比较表明,荷兰一般人群的健康状况偏好与其他欧洲国家不同。