J Varunkumar, Davis Prem, Ramanathan T, Prabu V
Department of Otorhinolaryngology, Sri Venkateswaraa Medical College Hospital and Research Insitute, Chennai, India.
ENT Division, Central University of TamilNadu, Thiruvarur, India.
Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4216-4221. doi: 10.1007/s12070-024-04817-2. Epub 2024 Jun 20.
Allergic rhinitis is one of the most common and undertreated diseases in the world. In recent times, there has been increased development of non-sinus headaches among patients with allergic rhinitis. Various common endogenous molecules such as nitric oxide, calcitonin gene-related peptide, and histamine have been implicated in the development of migraines, which leads to the development of migraines among allergic rhinitis patients. The study aims to determine the prevalence of migraine among allergic rhinitis patients and to find the association between the various demographic factors and the presence of migraine. This cross-sectional study was conducted in the ENT department of a tertiary care hospital in Puducherry. All patients aged more than 18 years old with the symptoms of allergic rhinitis were included in the study. The study was conducted six months, from July 2023 to December 2023. ARIA classification is used to determine the severity of the allergic rhinitis, and, per International criteria for headache, was used to diagnose migraine. A total of 282 patients with allergic rhinitis participated in the study. The mean age of the patients was found to be 38.89 11.04 years. The prevalence of migraine among allergic rhinitis patients was found to be 69.1%-Economic status (39.4%). About 16.7% of the patients with diabetes were associated with migraine. The study showed a significant association between sex (p-0.006), age ( < 0.001), and socio-economic status (p-0.034) with the presence of migraine. The study also showed a significant association between the severity of allergic rhinitis and the presence of migraine (p-0.034) and the type of migraine (p-0.004). The study concludes that a significant proportion of the patients with allergic rhinitis were associated with migraine. So, clinicians should always screen for the presence of the migraine in all patients with allergic rhinitis to improve the patient's quality of life.
变应性鼻炎是世界上最常见且治疗不足的疾病之一。近年来，变应性鼻炎患者中非鼻窦性头痛的发病率有所增加。一氧化氮、降钙素基因相关肽和组胺等各种常见内源性分子与偏头痛的发生有关，这导致变应性鼻炎患者出现偏头痛。该研究旨在确定变应性鼻炎患者中偏头痛的患病率，并找出各种人口统计学因素与偏头痛存在之间的关联。这项横断面研究在本地治里一家三级护理医院的耳鼻喉科进行。所有年龄超过18岁且有变应性鼻炎症状的患者均纳入该研究。该研究于2023年7月至2023年12月进行了六个月。采用ARIA分类法确定变应性鼻炎的严重程度，并根据国际头痛标准诊断偏头痛。共有282例变应性鼻炎患者参与了该研究。患者的平均年龄为38.89±11.04岁。变应性鼻炎患者中偏头痛的患病率为69.1%——经济状况（39.4%）。约16.7%的糖尿病患者与偏头痛有关。该研究表明性别（p = 0.006）、年龄（p<0.001）和社会经济状况（p = 0.034）与偏头痛的存在之间存在显著关联。该研究还表明变应性鼻炎的严重程度与偏头痛的存在（p = 0.034）以及偏头痛的类型（p = 0.004）之间存在显著关联。该研究得出结论，相当一部分变应性鼻炎患者与偏头痛有关。因此，临床医生应始终对所有变应性鼻炎患者筛查偏头痛的存在情况，以提高患者的生活质量。
