淋巴结比率在预测颈部淋巴结阳性的甲状腺乳头状癌患者生化不完全临床反应中的应用
Utility of Lymph Node Ratio in Predicting Biochemical Incomplete Clinical Response in Patients with Papillary Ca thyroid with Positive Neck Node.
作者信息
Gontu Gopi Satya Sai Reddy, Das Rajjyoti, Rahman Tashnin, Das Ashok Kumar, Das Kishore, Das Anupam, Kakati Kaberi
机构信息
Department of Head & Neck Surgery, Dr Bhubneshwar Borooah Cancer Institute Guwahati, Guwahati, Assam India.
出版信息
Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4043-4049. doi: 10.1007/s12070-024-04777-7. Epub 2024 Jun 6.
BACKGROUND
with the requirement of aggressive follow-up in patients with biochemically incomplete response in patients of papillary ca. thyroid with neck node, a predictor for clinical response would be of great help for better treatment and follow-up planning.
AIM
To determine the utility of lymph-node ratio (central and lateral) as predictors for clinical response post total thyroidectomy and neck dissection.
MATERIALS AND METHODS
51 patients of papillary carcinoma thyroid with neck node were treated with surgery and RAI as per ATA guidelines and were analyzed for a median of 3 years. (Retrospective cohort analysis).
RESULTS
We did response evaluation, correlated clinical response with lymph-node ratios. We found a statistically significant relationship of lymph-node ratio with around a sensitivity and specificity of approximately 90% in predicting the biochemically incomplete response.
CONCLUSION
we conclude that lateral and central compartment ratios can be used in predicting the occurrence of biochemically incomplete response.
背景
对于甲状腺乳头状癌伴颈部淋巴结且生化反应不完全的患者，需要积极随访，临床反应预测指标将有助于更好地进行治疗和随访规划。
目的
确定淋巴结比率（中央区和侧区）作为全甲状腺切除术后及颈部清扫术后临床反应预测指标的效用。
材料与方法
51例甲状腺乳头状癌伴颈部淋巴结患者按照美国甲状腺协会（ATA）指南接受手术及放射性碘（RAI）治疗，并进行了中位时间为3年的分析。（回顾性队列分析）
结果
我们进行了反应评估，将临床反应与淋巴结比率相关联。我们发现淋巴结比率与生化反应不完全的预测之间存在统计学显著关系，敏感性和特异性约为90%。
结论
我们得出结论，侧区和中央区淋巴结比率可用于预测生化反应不完全的发生情况。
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