Wang Laura Y, Ganly Ian
Department of Surgery, Head & Neck Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Future Oncol. 2016 Apr;12(7):981-94. doi: 10.2217/fon.16.10. Epub 2016 Mar 7.
The significance of cervical lymph node metastases in differentiated thyroid cancer has been controversial and continues to evolve. Current staging systems consider nodal metastases to confer a poorer prognosis, particularly in older patients. Increasingly, the literature suggests that characteristics of the metastatic lymph nodes such as size and number are also prognostic. There is a growing trend toward less aggressive treatment of low-volume nodal disease. The aim of this review is to summarize the current literature and discuss prognostic and management implications of lymph node metastases in differentiated thyroid cancer.
分化型甲状腺癌中颈部淋巴结转移的意义一直存在争议且仍在不断演变。目前的分期系统认为淋巴结转移预示着较差的预后，尤其是在老年患者中。越来越多的文献表明，转移淋巴结的特征如大小和数量也具有预后价值。对于低负荷淋巴结疾病，采用侵袭性较小的治疗方法的趋势日益明显。本综述的目的是总结当前文献，并讨论分化型甲状腺癌中淋巴结转移的预后及管理意义。
