Varshini Amrutha, Anehosur Venkatesh, Joshi Vajendra K, Kumar Niranjan
Department of Oral and Maxillofacial Surgery, SDM Craniofacial Research Centre, SDM College of Dental Sciences and Hospital, Shri Dharmasthala Manjunatheshwara University, Dharwad, Karnataka 580009 India.
Department of Anaesthesiology, SDM Craniofacial Research Centre, SDM College of Dental Sciences and Hospital, Shri Dharmasthala Manjunatheshwara University, Dharwad, Karnataka 580009 India.
J Maxillofac Oral Surg. 2024 Oct;23(5):1072-1078. doi: 10.1007/s12663-022-01814-2. Epub 2022 Oct 31.
The primary objective is to estimate the blood loss following major surgery like neck dissection, resection of primary and reconstruction; secondarily to evaluate the incidence of blood transfusion, to assess various options of blood conservation to avert blood transfusions.
The data for the prospective study were obtained from 2017-2019. The predictor variables were drawn from demographic characteristics, biopsy report, haemoglobin status, comorbidities, staging, surgical planning, intraoperative and post-operative measures taken for blood loss assessment. Outcome variables were estimation of blood loss, incidence of blood transfusion and measures to avoid.
Thirty-eight patients 29 males (76.3%) comparison to nine females (23.6%) with 35 cases (92.1%) of oral squamous cell carcinoma. Average blood loss was 673.5 ml with a range of 400-807 ml. There was direct co-relation between the duration of surgery and amount of blood loss. In 76.3% patient's blood transfusion was avoided which is significant.
Though there is no single standardized method as the accuracy is still questionable. In this study blood loss and incidence of blood transfusion was low so as to promote the hypothesis of blood conservation and transfusion in major surgeries by various pre, intra and post-operative measures.
主要目的是估计诸如颈部清扫术、原发灶切除及重建等大手术后的失血量；其次是评估输血发生率，评估各种血液保护措施以避免输血。
前瞻性研究的数据取自2017年至2019年。预测变量来自人口统计学特征、活检报告、血红蛋白状态、合并症、分期、手术规划、术中及术后为评估失血量所采取的措施。结果变量为失血量估计、输血发生率及避免措施。
38例患者中，29例男性（76.3%），9例女性（23.6%），其中35例（92.1%）为口腔鳞状细胞癌。平均失血量为673.5毫升，范围为400至807毫升。手术时间与失血量之间存在直接相关性。76.3%的患者避免了输血，这一比例具有统计学意义。
尽管目前尚无单一的标准化方法，因为其准确性仍存在疑问。在本研究中，失血量和输血发生率较低，因此通过各种术前、术中和术后措施，支持了在大手术中进行血液保护和输血的假设。
