Association of Membranous Basal Cell Adenoma and Basal Cell Adenocarcinoma With Brooke-Spiegler Syndrome.

Basal cell adenoma (BCA) and basal cell adenocarcinoma (BCAC) are uncommon basaloid biphasic salivary gland tumors composed of basal and ductal cells. BCAC is differentiated from BCA by the presence of invasion in BCAC. In this paper, an 82-year-old woman presented with a palpable 3 cm immobile mass in her right parotid gland. A computed tomography (CT) scan showed two separate right parotid masses. She underwent a right parotidectomy, and the pathology showed multiple membranous BCAs and BCAC, which were highly suspicious for Brooke-Spiegler syndrome (BSS). This paper discusses BCA, BCAC, and their relationship with BSS.