Department of Pathology, University of Iowa, University of Iowa Carver College of Medicine, 5238 H Roy Carver Pavilion, 200 Hawkins Drive, Iowa City, IA 52242, USA.
Surg Pathol Clin. 2021 Mar;14(1):25-42. doi: 10.1016/j.path.2020.09.005. Epub 2021 Jan 5.
Basal cell adenoma (BCA) and basal cell adenocarcinoma (BCAC) are uncommon biphasic salivary gland tumors having morphologic similarities to other biphasic salivary gland neoplasms having differentiation toward the intercalated ducts of the salivary gland. Both tumors show mixtures of trabecular, tubular, solid, and membranous solid patterns. BCAC is separated from BCA primarily by the presence of invasion in the former. The diagnosis of BCA and BCAC is best carried out with hematoxylin and eosin-stained sections and careful attention to detail of tumors in the differential diagnosis, including adenoid cystic carcinoma, pleomorphic adenoma, and epithelial myoepithelial carcinoma.
基底细胞腺瘤(BCA)和基底细胞腺癌(BCAC)是少见的双相涎腺肿瘤,其形态学与其他具有涎腺闰管分化的双相涎腺肿瘤相似。两种肿瘤均显示出小梁状、管状、实性和膜性实性混合模式。BCAC 与 BCA 的主要区别在于前者存在浸润。BCA 和 BCAC 的诊断最好通过苏木精和伊红染色切片进行,并在鉴别诊断中仔细注意肿瘤的细节,包括腺样囊性癌、多形性腺瘤和上皮肌上皮癌。