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多系统萎缩小脑型的一例具有挑战性的病例报告:来自索马里的罕见病例报告。

A challenging case presentation of multiple system atrophy cerebellar type: A rare case report from Somalia.

作者信息

Sidow Nor Osman, Ibrahim Abdiwahid Ahmed, Ibrahim Ismail Gedi, Hassan Mohamed Sheikh, Mohamed Said Abdi

机构信息

Department of Neurology, Mogadishu-Somalia Turkey Recep Tayyip Erdoğan Training and Research Hospital, Mogadishu, Somalia.

Faculty of Medicine and Surgery, Jazeera Univesity, Mogadishu, Somalia.

出版信息

Radiol Case Rep. 2024 Sep 23;19(12):6183-6186. doi: 10.1016/j.radcr.2024.08.145. eCollection 2024 Dec.

Abstract

Multiple system atrophy is a rare and quickly progressing neurological condition characterized by autonomic failure, parkinsonism, or cerebellar ataxia. It is classified into two subtypes: MSA with predominant parkinsonism (MSA-P) and MSA with predominant cerebellar ataxia (MSA-C). We are presenting here a 54-year-old male with parkinsonism, ataxia, and dysarthria. He was diagnosed with parkinson disease and was given a maximum dose of levodopa but has not responded. After a close neurological evaluation with magnetic resonance imaging of the brain, which shows atrophy of the cerebellum and a brainstem with a hot cross bun sign of the pons, suggestive of multiple system atrophy, he was diagnosed with multiple system atrophy cerebellar type, which is the first time to have this diagnosis in Somalia, which is a low-resource country.

摘要

多系统萎缩是一种罕见且进展迅速的神经系统疾病,其特征为自主神经功能衰竭、帕金森综合征或小脑共济失调。它分为两个亚型:以帕金森综合征为主的多系统萎缩(MSA-P)和以小脑共济失调为主的多系统萎缩(MSA-C)。我们在此介绍一名54岁男性,他患有帕金森综合征、共济失调和构音障碍。他曾被诊断为帕金森病,并接受了最大剂量的左旋多巴治疗,但没有效果。经过详细的神经系统评估及脑部磁共振成像检查,结果显示小脑和脑干萎缩,脑桥有“热十字面包征”,提示多系统萎缩,他被诊断为多系统萎缩小脑型,这在资源匮乏的索马里是首次作出该诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de5c/11456811/f5baa242198a/gr1.jpg

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