Salichs Marta, Beasley Shea, Homedes Josep
Ecuphar Veterinaria SLU (Animalcare Group), Sant Cugat Del Vallés, Barcelona, Spain.
Sheaps Oy, Ojakkala, Finland.
Vet Dermatol. 2025 Feb;36(1):74-82. doi: 10.1111/vde.13304. Epub 2024 Oct 8.
Anal sac impaction is common in dogs. Manual expression may be effective, yet recurrence can be problematic. To facilitate physiological emptying of the sacs, it is important to maintain bulky stool consistency.
The study evaluated if supplementation with a complementary feed product formulated as a chew containing Bacillus velezensis C-3102 and fibre sources, reduced anal sac impaction recurrence.
Thirty-five client-owned dogs with anal sac impaction were enrolled.
Prospective, randomised, negative controlled field clinical trial with 22 dogs receiving the chew orally for 90 consecutive days and 13 dogs with no treatment. Dogs were evaluated on Day (D) 30, 60, 90 and 120 for the presence of clinical signs of anal sac impaction and the need to empty the sacs. Any animal that required manual expression of the sacs was classified as a failure and was withdrawn from the study.
The cumulative percentage of failures in the untreated group increased steadily from the first follow-up visit on D30 (15%) to the last visit on D120 (61.5%). However, in the group receiving the chew the cumulative percentage of failures increased at a much slower rate and stabilised at 19% from the D90 visit (last administration day) until the end of the study on D120, with statistically significant differences (p = 0.025). Animals receiving the chew also showed reduction in clinical signs.
The probiotic and fibre chew was a safe and effective management option for recurrent anal sac impaction in dogs.
肛门囊阻塞在犬类中很常见。手动挤压可能有效，但复发可能会带来问题。为促进肛门囊的生理性排空，保持粪便体积大且质地正常很重要。
本研究评估了补充一种含有解淀粉芽孢杆菌C-3102和纤维源的咀嚼型补充饲料产品是否能减少肛门囊阻塞的复发。
纳入了35只患有肛门囊阻塞的客户拥有的犬。
前瞻性、随机、阴性对照的现场临床试验，22只犬连续90天口服该咀嚼物，13只犬不接受治疗。在第30天、60天、90天和120天对犬进行评估，观察是否存在肛门囊阻塞的临床症状以及排空肛门囊的必要性。任何需要手动挤压肛门囊的动物都被归类为治疗失败，并退出研究。
未治疗组的失败累积百分比从第30天的首次随访（15%）稳步增加到第120天的最后一次随访（61.5%）。然而，接受咀嚼物治疗的组中，失败累积百分比的增加速度要慢得多，从第90天（最后给药日）到第120天研究结束时稳定在19%，差异有统计学意义（p = 0.025）。接受咀嚼物治疗的动物临床症状也有所减轻。
益生菌和纤维咀嚼物是治疗犬复发性肛门囊阻塞的一种安全有效的管理选择。
