CSE Department, Punjab Engineering College (Deemed to be University), Chandigarh, India.
Biomed Phys Eng Express. 2024 Sep 30;10(6). doi: 10.1088/2057-1976/ad7bc0.
Cervical cancer remains a major global health challenge, accounting for significant morbidity and mortality among women. Early detection through screening, such as Pap smear tests, is crucial for effective treatment and improved patient outcomes. However, traditional manual analysis of Pap smear images is labor-intensive, subject to human error, and requires extensive expertise. To address these challenges, automated approaches using deep learning techniques have been increasingly explored, offering the potential for enhanced diagnostic accuracy and efficiency. This research focuses on improving cervical cancer detection from Pap smear images using advanced deep-learning techniques. Specifically, we aim to enhance classification performance by leveraging Transfer Learning (TL) combined with an attention mechanism, supplemented by effective preprocessing techniques. Our preprocessing pipeline includes image normalization, resizing, and the application of Histogram of Oriented Gradients (HOG), all of which contribute to better feature extraction and improved model performance. The dataset used in this study is the Mendeley Liquid-Based Cytology (LBC) dataset, which provides a comprehensive collection of cervical cytology images annotated by expert cytopathologists. Initial experiments with the ResNet model on raw data yielded an accuracy of 63.95%. However, by applying our preprocessing techniques and integrating an attention mechanism, the accuracy of the ResNet model increased dramatically to 96.74%. Further, the Xception model, known for its superior feature extraction capabilities, achieved the best performance with an accuracy of 98.95%, along with high precision (0.97), recall (0.99), and F1-Score (0.98) on preprocessed data with an attention mechanism. These results underscore the effectiveness of combining preprocessing techniques, TL, and attention mechanisms to significantly enhance the performance of automated cervical cancer detection systems. Our findings demonstrate the potential of these advanced techniques to provide reliable, accurate, and efficient diagnostic tools, which could greatly benefit clinical practice and improve patient outcomes in cervical cancer screening.
宫颈癌仍然是一个重大的全球健康挑战,给女性带来了巨大的发病率和死亡率。通过筛查,如巴氏涂片检查,早期发现对于有效的治疗和改善患者预后至关重要。然而,传统的巴氏涂片图像手动分析既劳动密集型,又容易出现人为错误,且需要广泛的专业知识。为了解决这些挑战,越来越多的研究人员探索使用深度学习技术的自动化方法,为提高诊断准确性和效率提供了潜力。本研究专注于使用先进的深度学习技术提高从巴氏涂片图像中检测宫颈癌的能力。具体来说,我们旨在通过利用迁移学习(TL)结合注意力机制来提高分类性能,同时辅以有效的预处理技术。我们的预处理管道包括图像归一化、调整大小以及应用方向梯度直方图(HOG),所有这些都有助于更好地提取特征和提高模型性能。本研究使用的数据集是 Mendeley 基于液体的细胞学(LBC)数据集,它提供了由专家细胞学专家注释的全面的宫颈细胞学图像集合。在原始数据上使用 ResNet 模型的初步实验产生了 63.95%的准确率。然而,通过应用我们的预处理技术并集成注意力机制,ResNet 模型的准确率大大提高到了 96.74%。此外,Xception 模型以其卓越的特征提取能力而闻名,在预处理数据上使用注意力机制实现了最佳性能,准确率为 98.95%,同时具有高精确度(0.97)、高召回率(0.99)和 F1 分数(0.98)。这些结果突出了结合预处理技术、TL 和注意力机制的有效性,可显著提高自动化宫颈癌检测系统的性能。我们的研究结果表明,这些先进技术具有提供可靠、准确和高效诊断工具的潜力,这将极大地有益于临床实践并改善宫颈癌筛查中的患者预后。