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优化 HPV 相关癌症防护:HPV 疫苗接种的益处与挑战。

Optimizing Protection Against HPV-Related Cancer: Unveiling the Benefits and Overcoming Challenges of HPV Vaccination.

出版信息

Pediatr Ann. 2024 Oct;53(10):e372-e377. doi: 10.3928/19382359-20240811-02. Epub 2024 Oct 1.

DOI:10.3928/19382359-20240811-02
PMID:39377820
Abstract

Human papillomavirus (HPV) vaccine is an underutilized tool in cancer prevention. HPV vaccine completion rates in adolescents age 13 to 15 years remain low at 59%. The HPV vaccine can prevent more than 90% of cases of cancer caused by HPV, including cervical, oropharyngeal, anal, penile, vulvar, and vaginal. HPV vaccine is very safe and effective, as demonstrated by numerous large-scale studies. Practice-based strategies can improve vaccination rates, such as having providers give a strong presumptive recommendation for the vaccine, using motivational interviewing for hesitant families, and using electronic health record reminders to prompt providers to offer it, among other interventions. Offering HPV vaccine starting at age 9 years is another evidence-based strategy to improve HPV vaccine completion rates, which has been shown to be acceptable to both providers and parents. .

摘要

人乳头瘤病毒(HPV)疫苗是癌症预防中未充分利用的工具。13 至 15 岁青少年 HPV 疫苗接种完成率仍处于较低水平,为 59%。HPV 疫苗可预防 HPV 引起的 90%以上癌症,包括宫颈癌、口咽癌、肛门癌、阴茎癌、外阴癌和阴道癌。大量大规模研究证明,HPV 疫苗非常安全有效。基于实践的策略可以提高疫苗接种率,例如让提供者强烈推荐疫苗,对犹豫不决的家庭使用动机性访谈,以及使用电子健康记录提醒来提示提供者提供疫苗等。从 9 岁开始提供 HPV 疫苗是另一种提高 HPV 疫苗接种完成率的基于证据的策略,已被证明既被提供者又被父母接受。

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