Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Curr Biol. 2024 Oct 7;34(19):R904-R906. doi: 10.1016/j.cub.2024.08.055.
Placebo analgesia is well documented in human populations but remains relatively under-researched in rodent models. Now researchers have engineered robust circuit-based placebo analgesia in mice and identified pathways mediating the effect of expectations, offering new insights into harnessing placebo for pain management.
安慰剂镇痛在人类群体中已有充分的记录,但在啮齿动物模型中仍相对研究不足。现在,研究人员已经在小鼠中设计了基于电路的强大安慰剂镇痛,并确定了介导预期效应的途径,为利用安慰剂进行疼痛管理提供了新的见解。