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Placebo analgesia: psychological and neurobiological mechanisms.安慰剂镇痛：心理和神经生物学机制。
Pain. 2013 Apr;154(4):511-514. doi: 10.1016/j.pain.2013.02.002. Epub 2013 Feb 13.
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Pain beyond biology.超越生物学的疼痛。
Pain. 2013 Nov;154(11):2571-2572. doi: 10.1016/j.pain.2013.07.003. Epub 2013 Jul 9.
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Response to the letter to the editor by L.A. Avila.对L.A. 阿维拉致编辑信的回复。
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Placebo analgesia: understanding the mechanisms.安慰剂镇痛：理解其机制
Pain Manag. 2015;5(2):89-96. doi: 10.2217/pmt.15.3.
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Brain and body: Implanting a placebo in the brain to alleviate pain.大脑与身体：在大脑中植入安慰剂以减轻疼痛。
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Temporal expectancy induced by the mere possession of a placebo analgesic affects placebo analgesia: preliminary findings from a randomized controlled trial.仅仅拥有安慰剂镇痛剂所引起的时间预期会影响安慰剂镇痛效果：一项随机对照试验的初步发现。
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Eur J Pain. 2025 Oct;29(9):e70113. doi: 10.1002/ejp.70113.
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Pilot Feasibility Stud. 2025 Aug 20;11(1):111. doi: 10.1186/s40814-025-01692-8.
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Opioids diminish the placebo antidepressant response: Observational post hoc findings from a randomized controlled ketamine trial.阿片类药物会减弱安慰剂的抗抑郁反应：一项随机对照氯胺酮试验的事后观察结果。
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The Two Sides of Placebo Analgesia: Differential Functional Connectivity Reveals Mechanisms of Placebo Analgesic Response.安慰剂镇痛的两面：差异性功能连接揭示安慰剂镇痛反应的机制
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Perceiving immunity, predicting somatic symptoms: Validation of the 'Perceived Immunity' scale and its association with daily health.感知免疫力，预测躯体症状：“感知免疫力”量表的验证及其与日常健康的关联
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Opioids Diminish the Placebo Antidepressant Response: A Post Hoc Analysis of a Randomized Controlled Ketamine Trial.阿片类药物会削弱安慰剂的抗抑郁反应：一项关于氯胺酮的随机对照试验的事后分析
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Effects of acupuncture versus placebo on clinical status and potential specific effects in Fibromyalgia: an umbrella review of 11 meta-analyses.针刺疗法与安慰剂对纤维肌痛临床状况及潜在特定效应的影响：11项荟萃分析的伞状综述
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本文引用的文献

1
Functional connectivity of the frontoparietal network predicts cognitive modulation of pain.额顶网络的功能连接预测疼痛的认知调节。
Pain. 2013 Mar;154(3):459-467. doi: 10.1016/j.pain.2012.12.004. Epub 2012 Dec 20.
2
Personality trait predictors of placebo analgesia and neurobiological correlates.人格特质预测安慰剂镇痛和神经生物学相关性。
Neuropsychopharmacology. 2013 Mar;38(4):639-46. doi: 10.1038/npp.2012.227. Epub 2012 Nov 16.
3
Catechol-O-methyltransferase val158met polymorphism predicts placebo effect in irritable bowel syndrome.儿茶酚氧位甲基转移酶 val158met 多态性可预测肠易激综合征的安慰剂效应。
PLoS One. 2012;7(10):e48135. doi: 10.1371/journal.pone.0048135. Epub 2012 Oct 23.
4
Nonconscious activation of placebo and nocebo pain responses.安慰剂和反安慰剂疼痛反应的无意识激活。
Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15959-64. doi: 10.1073/pnas.1202056109. Epub 2012 Sep 10.
5
Brain networks predicting placebo analgesia in a clinical trial for chronic back pain.大脑网络预测慢性背痛临床试验中的安慰剂镇痛效果。
Pain. 2012 Dec;153(12):2393-2402. doi: 10.1016/j.pain.2012.08.008. Epub 2012 Sep 15.
6
White matter integrity of the descending pain modulatory system is associated with interindividual differences in placebo analgesia.下行疼痛调制系统的白质完整性与安慰剂镇痛的个体间差异有关。
Pain. 2012 Nov;153(11):2210-2217. doi: 10.1016/j.pain.2012.07.010. Epub 2012 Sep 5.
7
Plasma noradrenaline and state anxiety levels predict placebo response in learned immunosuppression.血浆去甲肾上腺素和状态焦虑水平预测习得性免疫抑制中的安慰剂反应。
Clin Pharmacol Ther. 2012 Feb;91(2):220-6. doi: 10.1038/clpt.2011.214. Epub 2011 Dec 14.
8
Nonopioid placebo analgesia is mediated by CB1 cannabinoid receptors.非阿片类安慰剂镇痛是由 CB1 cannabinoid 受体介导的。
Nat Med. 2011 Oct 2;17(10):1228-30. doi: 10.1038/nm.2435.
9
Variability in placebo analgesia and the role of fear of pain--an ERP study.安慰剂镇痛的变异性和疼痛恐惧的作用——一项 ERP 研究。
Pain. 2011 Oct;152(10):2405-2412. doi: 10.1016/j.pain.2011.07.010. Epub 2011 Aug 27.
10
The effect of treatment expectation on drug efficacy: imaging the analgesic benefit of the opioid remifentanil.治疗期望对药物疗效的影响：阿片类药物瑞芬太尼的镇痛获益的成像研究。
Sci Transl Med. 2011 Feb 16;3(70):70ra14. doi: 10.1126/scitranslmed.3001244.

Placebo analgesia: psychological and neurobiological mechanisms.

作者信息

Colloca Luana, Klinger Regine, Flor Herta, Bingel Ulrike

机构信息

National Center for Complementary and Alternative Medicine (NCCAM), National Institute of Mental Health (NIMH) and Clinical Center, Department of Bioethics, National Institutes of Health (NIH), Bethesda, MD, USA Outpatient Clinic of Behavior Therapy, Department of Psychology, University of Hamburg, Hamburg, Germany Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany NeuroImage Nord, Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

出版信息

Pain. 2013 Apr;154(4):511-514. doi: 10.1016/j.pain.2013.02.002. Epub 2013 Feb 13.

DOI:10.1016/j.pain.2013.02.002
PMID:23473783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3626115/
Abstract
摘要