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神经性厌食症患者在医学营养治疗中的特征和结局:一项机构研究并文献复习。

Characteristics and outcome of patients with anorexia nervosa on medical nutritional therapy: an institutional study with review of literature.

机构信息

Dietetics Department, National University Hospital, Singapore.

Department of Paediatrics, National University Hospital, Singapore.

出版信息

Singapore Med J. 2024 Oct 1;65(10):564-570. doi: 10.4103/singaporemedj.SMJ-2022-062. Epub 2023 Nov 29.

DOI:10.4103/singaporemedj.SMJ-2022-062
PMID:39379033
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11575724/
Abstract

INTRODUCTION

Eating disorders (EDs) are debilitating mental illnesses that can lead to significant medical complications from malnutrition. Eating disorders are on the rise in Asia and the prevalence is expected to increase. The aim of this study was to understand the characteristics of local patients and evaluate our current inpatient nutritional rehabilitation protocol for anorexia nervosa (AN).

METHODS

Retrospective descriptive data were gathered from 47 patients diagnosed with AN. Patients with admissions were further stratified according to their nutritional management based on whether they were on the AN protocol or standard hospital care. Data on their rate of weight gain, length of stay and calorie prescription were collected.

RESULTS

Similar to previous studies, the majority of AN patients were female (96.7%). However, the age at presentation of AN in this study, as compared with previous local studies, had decreased (14 vs. 16 years). We also found that patients on the AN protocol were prescribed a higher amount of calories than those given standard care (2,700 vs. 2,317 calories). Patients on the AN protocol achieved a higher rate of weight gain per week (1.15 vs. 0.29 kg) and had a shorter length of hospital stay (23 vs. 36 days).

CONCLUSION

Patients with AN appear to be presenting at a younger age. Medical stabilisation of AN patients can be achieved more quickly through a higher calorie inpatient AN treatment protocol. Future local studies examining actual calorie consumption, its effect on weight gain trajectory, severity of refeeding syndrome and time to remission will be beneficial.

摘要

简介

饮食失调(ED)是一种使人虚弱的精神疾病,可能会因营养不良而导致严重的医疗并发症。饮食失调在亚洲呈上升趋势,预计患病率将会增加。本研究旨在了解本地患者的特点,并评估我们目前用于神经性厌食症(AN)的住院营养康复方案。

方法

从 47 名被诊断为 AN 的患者中收集回顾性描述性数据。根据他们是否遵循 AN 方案或标准医院护理,将入院患者进一步根据其营养管理进行分层。收集了他们的体重增加率、住院时间和卡路里处方的数据。

结果

与之前的研究相似,大多数 AN 患者为女性(96.7%)。然而,与之前的本地研究相比,本研究中 AN 的发病年龄有所降低(14 岁对 16 岁)。我们还发现,遵循 AN 方案的患者比接受标准护理的患者开的卡路里更高(2700 对 2317 卡路里)。遵循 AN 方案的患者每周体重增加率更高(1.15 对 0.29 公斤),住院时间更短(23 对 36 天)。

结论

AN 患者似乎呈现出更年轻的发病年龄。通过更高热量的住院 AN 治疗方案,AN 患者的医疗稳定可以更快地实现。未来的本地研究,检查实际卡路里的摄入量、其对体重增加轨迹的影响、再喂养综合征的严重程度和缓解时间,将是有益的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8807/11575724/b92984ba9ceb/SMJ-65-564-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8807/11575724/b92984ba9ceb/SMJ-65-564-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8807/11575724/b92984ba9ceb/SMJ-65-564-g001.jpg

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Incidence of anorexia nervosa in young people in the UK and Ireland: a national surveillance study.英国和爱尔兰年轻人神经性厌食症的发病率:一项全国性监测研究。
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