Faculty of Health Sciences, University Of Buea, Buea, Cameroon.
Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
BMC Nephrol. 2024 Oct 8;25(1):335. doi: 10.1186/s12882-024-03778-6.
Reduced quality of life is associated with shorter survival in chronic illnesses. However, the health-related quality of life (HRQOL) and social reinsertion of patients on maintenance haemodialysis is much more underappreciated in resource-limited countries such as Cameroon.
A hospital-based cross-sectional study was carried out from February 22nd to May 20th, 2022, in 4 government-funded haemodialysis centres in three randomly selected regions of Cameroon. Patients received twice-weekly dialysis sessions. Social reinsertion and HRQOL were assessed using a structured questionnaire and the kidney disease quality of life instrument (KDQOL-36™). HRQOL scores < 50 were categorized as low, while scores > 50 reflected better HRQOL. Data were analysed using the software statistical package for Social Sciences version 25.0. Statistical significance was set at a p value < 0.05.
The study included 434 patients. The mean age was 48.33 (13.55) years, 65.7% (285/434) were male, 62.3% (269/434) had no monthly income, and the mean dialysis vintage was 3.74 (3.83) years. The mean HRQOL score was 44.34 (9.77), and 76.2% (325/434) had HRQOL scores < 50). Overall HRQOL was associated with older age (aOR: 2.344, CI 1.089-5.04). After the initiation of maintenance haemodialysis, 67.1% (49/73) of students dropped out of school. The main reason for school absenteeism and unemployment was physical insufficiency, with 82.4% (19/24) and 52.4% (75/144), respectively. There were no promotions or marriages after initiation; 51% (221/434) of relationships with relatives and friends were affected negatively, while 83.3% (66/79) of those of marriageable ages could not find suitors. The social participation score was poor in 61.5% (267/434) of participants. There was an association between low QOL and social participation (p = 0.009).
The HRQOL of patients on maintenance haemodialysis is greatly reduced, especially their physical health status. Older age was a determinant of low QOL. Additionally, social reinsertion remains poor due to adverse changes that occur to these patients and their families after dialysis initiation.
Not applicable.
生活质量下降与慢性病患者的生存时间缩短有关。然而，在资源有限的国家，如喀麦隆，患者接受维持性血液透析治疗的健康相关生活质量（HRQOL）和社会重新融入情况则更加被低估。
这是一项 2022 年 2 月 22 日至 5 月 20 日在喀麦隆三个随机选定地区的 4 家政府资助的血液透析中心进行的基于医院的横断面研究。患者每周接受两次透析。使用结构化问卷和肾脏病生活质量量表（KDQOL-36™）评估社会重新融入和 HRQOL。HRQOL 评分<50 分被归类为低，而评分>50 分则反映了更好的 HRQOL。使用社会科学统计软件包 25.0 进行数据分析。统计学意义设定为 p 值<0.05。
该研究纳入了 434 名患者。平均年龄为 48.33（13.55）岁，65.7%（285/434）为男性，62.3%（269/434）无月收入，平均透析龄为 3.74（3.83）年。平均 HRQOL 评分为 44.34（9.77），76.2%（325/434）的 HRQOL 评分<50）。总体 HRQOL 与年龄较大有关（OR：2.344，CI 1.089-5.04）。开始维持性血液透析后，67.1%（49/73）的学生辍学。学业和失业的主要原因是身体不适，分别占 82.4%（19/24）和 52.4%（75/144）。开始透析后没有晋升或结婚；51%（221/434）的亲属和朋友关系受到负面影响，而 83.3%（66/79）的适婚年龄的人找不到对象。61.5%（267/434）的参与者社会参与评分较差。生活质量低与社会参与有关（p=0.009）。
接受维持性血液透析治疗的患者的 HRQOL 大大降低，尤其是他们的身体健康状况。年龄较大是生活质量低的决定因素。此外，由于透析开始后这些患者及其家庭发生的不利变化，社会重新融入仍然较差。
不适用。
