Wycoff Andrea M, Miller Mary Beth, Trull Timothy J
Department of Psychiatry, University of Missouri, Columbia, Missouri, USA.
Department of Psychological Sciences, University of Missouri, Columbia, Missouri, USA.
Alcohol Clin Exp Res (Hoboken). 2024 Nov;48(11):2099-2112. doi: 10.1111/acer.15448. Epub 2024 Oct 8.
Poor sleep is common in the context of cannabis use, but experimental and daily-life studies provide mixed evidence for whether cannabis use helps or disturbs same-night sleep. Despite a high prevalence of co-use of alcohol and cannabis, most studies of cannabis use and sleep do not consider alcohol use. We sought to add to this literature by examining associations between cannabis and sleep in the context of alcohol co-use and to examine these associations bidirectionally using ecological momentary assessment.
Participants were 88 adults reporting cannabis use at least 3×/week and simultaneous alcohol and cannabis use at least 2×/week. For 14 days, participants completed morning surveys assessing hours slept and perceived sleep quality from the night before. In morning surveys, random surveys, and substance-specific surveys, participants also reported on alcohol and cannabis craving, use, and amounts.
Primary results from multilevel models demonstrated that cannabis use was not independently associated with sleep (duration or quality). However, cannabis use attenuated alcohol's negative effects on sleep quality.
Results question the utility of cannabis use to improve sleep but highlight the attenuated negative effects of alcohol as a potential reinforcer of alcohol-cannabis co-use. Future work should continue to consider polysubstance use and integrate additional self-report and objective measures of sleep health to further clarify how cannabis use affects sleep.
在大麻使用的背景下,睡眠质量差很常见,但实验研究和日常生活研究对于大麻使用是有助于还是干扰夜间睡眠提供了相互矛盾的证据。尽管酒精和大麻共同使用的情况很普遍,但大多数关于大麻使用与睡眠的研究并未考虑酒精使用情况。我们试图通过研究在酒精共同使用的背景下大麻与睡眠之间的关联来补充这方面的文献,并使用生态瞬时评估法双向研究这些关联。
参与者为88名成年人,他们报告每周至少使用大麻3次,且每周至少同时使用酒精和大麻2次。在14天的时间里,参与者完成了早晨的调查问卷,评估前一晚的睡眠时间和睡眠质量。在早晨的调查问卷、随机调查问卷以及特定物质调查问卷中,参与者还报告了对酒精和大麻的渴望程度、使用情况及用量。
多层次模型的主要结果表明,大麻使用与睡眠(时长或质量)并无独立关联。然而,大麻使用减弱了酒精对睡眠质量的负面影响。
研究结果对使用大麻改善睡眠的效用提出了质疑,但突出了酒精负面影响的减弱,这可能是酒精 - 大麻共同使用的一个强化因素。未来的研究应继续考虑多物质使用情况,并纳入更多关于睡眠健康的自我报告和客观测量方法,以进一步阐明大麻使用如何影响睡眠。