Federman Sharon Seelman, Jenkins Erin, Wilson Cullen, DeLaGarza Arturo, Schwensohn Colin, Schneider Benjamin, Nsubuga Johnson, Literman Robert, Wellman Allison, Whitney Brooke M, Bell Rebecca L, Harris-Garner Kerri, McKenna Crystal, Brillhart Darcy, Cross Merri, Rueber Kurt, Schlichte Thao, Oni Kemi, Adams Jennifer, Crosby Alvin J, Bazaco Michael C, Gieraltowski Laura, Nolte Kurt, Viazis Stelios
Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, MD, USA.
Office of Regulatory Affairs, Food and Drug Administration, Portland, ME, USA.
Food Control. 2024 Dec;166. doi: 10.1016/j.foodcont.2024.110733. Epub 2024 Jul 15.
In 2022, the Food and Drug Administration (FDA), the Centers for Disease Control and Prevention (CDC), and state health and regulatory partners investigated an outbreak of serovar Typhimurium infections linked to cantaloupes from southwest Indiana, resulting in 87 ill persons and 32 hospitalizations reported in 11 states. Epidemiologic and traceback evidence confirmed cantaloupe as the vehicle for these infections. Based on records collected by FDA, traceback of cantaloupe exposures for 14 ill people converged on a packing house in southwest Indiana, which supplied cantaloupe to eight of the 11 points of service where ill people purchased cantaloupe. isolates were recovered from environmental samples collected by FDA from three growers and a packing house in southwest Indiana. Whole genome sequencing analyses of these isolates found that isolates collected from one grower matched the Typhimurium outbreak strain, and samples collected from the other two growers and the packing house matched a 2020 Newport outbreak strain. State and federal public health and agricultural partners identified potential conditions and practices that could have possibly resulted in the contamination of cantaloupe, including the presence of spp. in on-farm, post-harvest, and off-farm environments. This is the third outbreak of salmonellosis confirmed to be linked to melons, sourced from southwest Indiana in the last decade. The 2012, 2020, and 2022 outbreaks of reoccurring and persisting strains of illustrate the need for additional efforts to determine the source and extent of environmental contamination in the melon growing region of southwest Indiana and for outreach and education to help promote practices to reduce contamination of melons.
2022年，美国食品药品监督管理局（FDA）、疾病控制与预防中心（CDC）以及州卫生与监管合作伙伴对一起与印第安纳州西南部哈密瓜相关的鼠伤寒血清型感染疫情展开了调查，此次疫情导致11个州报告了87人患病，32人住院。流行病学和溯源证据证实哈密瓜是这些感染的传播媒介。根据FDA收集的记录，对14名患病人员的哈密瓜接触情况进行溯源后发现，源头集中在印第安纳州西南部的一家包装厂，这家包装厂为11个患病人员购买哈密瓜的服务点中的8个供应了哈密瓜。从FDA在印第安纳州西南部的3个种植者和1家包装厂采集的环境样本中分离出了菌株。对这些分离株进行的全基因组测序分析发现，从1个种植者处采集的分离株与鼠伤寒疫情菌株匹配，从另外2个种植者和包装厂采集的样本与2020年纽波特疫情菌株匹配。州和联邦公共卫生及农业合作伙伴确定了可能导致哈密瓜污染的潜在条件和做法，包括在农场、收获后和农场外环境中存在某些菌种。这是过去十年中第三次确诊与甜瓜相关的沙门氏菌病疫情，源头均来自印第安纳州西南部。2012年、2020年和2022年反复出现且持续存在的菌株引发的疫情表明，需要做出更多努力来确定印第安纳州西南部甜瓜种植区环境污染的来源和程度，并开展宣传和教育活动，以促进采取减少甜瓜污染的做法。
