The effect of microbiome on social spacing in depends on genetic background and sex.

The gut microbiome modulates many essential functions including metabolism, immunity, and behaviour. Specifically, within behaviour, social behaviours such as sociability, aggregation, mating preference, avoidance, oviposition, and aggression are known to be regulated in part by this host-microbiome relationship. Here, we show the microbiome's role in the determination of social spacing in a sex- and genotype-specific manner. Future work can be done on characterizing the microbiome in each of these fly strains to identify the species of microbes present as well as their abundance.