Fernandes Rodney A, Moharana Sanjita, Choudhary Priyanka, Ranjan Ravikant S
Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400 076, Maharashtra, India.
Chem Commun (Camb). 2024 Oct 24;60(86):12561-12564. doi: 10.1039/d4cc03882g.
A metal, ligand and solvent-free three component reaction of 1-aryl-1,3-butadienes, CS and amine has been developed. In this process, readily available CS and secondary amines were used for C-N and C-S bonds giving allyl dithiocarbamates with notable Markovnikov selectivity, mild reaction conditions, simple operation and compatibility with various functional groups (37 examples). This is first case of dithiocarbamic acid addition to an unsymmetrical 1,3-diene system.
已开发出一种1-芳基-1,3-丁二烯、CS和胺的无金属、无配体和无溶剂的三组分反应。在此过程中，使用易于获得的CS和仲胺形成C-N键和C-S键，以显著的马氏选择性得到烯丙基二硫代氨基甲酸盐，反应条件温和，操作简单且与各种官能团兼容（37个实例）。这是二硫代氨基甲酸加成到不对称1,3-二烯体系的首例。
