Espinosa-Sánchez Astrid, Montaño-Estrada Luis Felipe, Rendón-Huerta Erika Patricia, Navarrete-Peón Alberto, Gómez-Aldapa Carlos Alberto, Muñóz-Pérez Víctor Manuel, Castro-Rosas Javier
Centro de Investigaciones Químicas, Instituto de Ciencias Básicas e Ingeniería, Universidad Autónoma del Estado de Hidalgo, Mineral de la Reforma, México.
Laboratorio de Inmunobiología, Departamento de Biología Celular y Tisular, Facultad de Medicina, Ciudad Universitaria, Ciudad de México, México.
J Med Food. 2024 Dec;27(12):1158-1167. doi: 10.1089/jmf.2024.0130. Epub 2024 Oct 9.
Most gastric cancers (95%) are related to an initial infection worldwide. Treatments against this pathogen include a mix of antibiotics, antimicrobials, and proton-pump inhibitors. Over time, mutated, generating resistance to treatments and making it hard to combat its infection. The purpose of this review is , commonly known as hibiscus, as a potential agent for anti- activity. Scientific interest has increased toward plant-derived bioactive compounds, which have the ability to enhance the antibiotic effect and can lead to the development of new drugs, such is the case for In general, studies show that natural products, such as plant-derived bioactive compounds, can be used as alternative treatments from natural origin against the pathogen. The specific action mechanism of these bioactive compounds is still controversial, but it is suggested that they have an anti-inflammatory effect, and they also act as antibiotic coadjutants. Research has been conducted regarding different bioactive compounds such as polyphenols, epicatechins, alkaloids, and caryophyllenes. contains several of these compounds; therefore, more studies are needed to establish its effect against .
全球大多数胃癌（95%）与初始感染有关。针对这种病原体的治疗包括抗生素、抗菌药物和质子泵抑制剂的组合。随着时间的推移，病原体发生突变，产生了对治疗的抗性，使其感染难以对抗。本综述的目的是研究芙蓉（通常称为木槿）作为一种潜在的抗活性药物。对植物源生物活性化合物的科学兴趣有所增加，这些化合物能够增强抗生素作用，并可导致新药的开发，就是这样。一般来说，研究表明，天然产物，如植物源生物活性化合物，可作为天然来源的替代疗法来对抗病原体。这些生物活性化合物的具体作用机制仍存在争议，但有人认为它们具有抗炎作用，并且还可作为抗生素佐剂。已经对不同的生物活性化合物进行了研究，如多酚、表儿茶素、生物碱和石竹烯。木槿含有其中几种化合物；因此，需要更多的研究来确定其对该病原体的作用。
