Zhou Fang, Sun Yi-Tong, Zheng Hong-Xin, Xiao Jing-Dong
The First Clinical College, Liaoning University of Traditional Chinese Medicine, Shenyang 110032, Liaoning Province, China.
School of Basic Medical Sciences, Liaoning University of Traditional Chinese Medicine, Shenyang 110032, Liaoning Province, China.
World J Gastroenterol. 2025 Aug 7;31(29):110133. doi: 10.3748/wjg.v31.i29.110133.
This article focuses on the clinical efficacy and mechanism of action of heat-clearing and detoxifying traditional Chinese medicines (TCMs) in the treatment of erosive gastritis, providing a reference for the treatment of this disease. In the clinical treatment of erosive gastritis, TCM combinations such as Qing Gastric San, Semixia Diarrheal Heart Soup, and single-flavored heat-clearing and detoxifying drugs such as dandelion and Huanglian have specific efficacies and effectively improve the patient's symptoms, including killing or inhibiting , reducing inflammatory reactions, protecting the gastric mucosa, inhibiting gastric acid secretion, regulating gastrointestinal hormones, and regulating immune function, playing therapeutic roles through multi-level and multi-target mechanisms. Thus, heat-clearing and detoxifying TCMs have broad application prospects in clinical practice for erosive gastritis.
本文聚焦于清热解毒类中药治疗糜烂性胃炎的临床疗效及作用机制，为该病的治疗提供参考。在糜烂性胃炎的临床治疗中，清胃散、半夏泻心汤等中药复方以及蒲公英、黄连等单味清热解毒药具有特定疗效，能有效改善患者症状，包括杀灭或抑制、减轻炎症反应、保护胃黏膜、抑制胃酸分泌、调节胃肠激素以及调节免疫功能，通过多层次、多靶点机制发挥治疗作用。因此，清热解毒类中药在糜烂性胃炎的临床实践中具有广阔的应用前景。
