Health Economics Unit, Stoke on Trent, UK
Ipsos MORI UK Ltd, London, UK.
BMJ Open Respir Res. 2024 Oct 9;11(1):e001914. doi: 10.1136/bmjresp-2023-001914.
Treatment options for chronic obstructive pulmonary disease (COPD) are numerous but adherence remains a key challenge. We performed a discrete choice experiment (DCE) of patients' preferences in accessing care for the management of COPD. The aim of this study was to understand patients' preferences for modes of accessing care for the management of COPD. This piece of work was then used to inform resource allocation decisions in five integrated care systems (ICSs) in England.
People with diagnosed COPD in five ICSs were invited to complete an online survey from August to September 2022. An experimental design built on the principles of minimal overlap, level balance and orthogonality was used to create 20 sets of 11 scenarios for participants to assess. Participants were presented with three hypothetical options and asked to select their most preferred or state that none was preferred. Data were analysed using a hierarchal Bayes algorithm.
Of 82 639 patients with COPD in the study area, 520 completed the survey. The mean health-related quality of life score derived using EuroQol 5-Dimensions 5-Level was 0.57 (0.29). The attributes assigned greatest importance were treatment outcomes, treatment delivery and the type of staff who deliver treatment. Mean utility level scores were substantially higher for little relief (22.75 (SD 78.80)) or some relief from symptoms (20.67 (46.77)) than for complete relief (‒43.42 (83.03)). Of the treatment delivery options, in-person individual appointments were preferred (mean utility score 48.34 (SD 48.14)), and care being provided by healthcare professionals was viewed as very important (77.50 (64.39)).
The DCE approach can help resource allocation decisions by indicating attributes most important to patients and trade-offs they are willing to make in treatment access and delivery.
慢性阻塞性肺疾病(COPD)的治疗选择众多,但患者的依从性仍然是一个关键挑战。我们对患者在 COPD 管理中寻求治疗的偏好进行了离散选择实验(DCE)。本研究旨在了解患者对 COPD 管理中寻求治疗的偏好模式。这项工作随后用于为英格兰的五个综合护理系统(ICS)的资源分配决策提供信息。
五个 ICS 中诊断为 COPD 的患者被邀请在 2022 年 8 月至 9 月期间在线完成调查。参与者被呈现三个假设的选择,并被要求选择他们最偏好的一个或表示都不偏好。采用基于最小重叠、水平平衡和正交性原则的实验设计来创建 20 组 11 个情景供参与者评估。数据使用分层贝叶斯算法进行分析。
在研究区域内,有 82639 名 COPD 患者,其中 520 名完成了调查。使用 EuroQol 5-Dimensions 5-Level 得出的平均健康相关生活质量评分是 0.57(0.29)。被赋予最大重要性的属性是治疗结果、治疗提供方式和提供治疗的人员类型。从症状中获得少许缓解(22.75(78.80))或一些缓解(20.67(46.77))的平均效用水平评分远高于完全缓解(-43.42(83.03))。在治疗提供方式中,个人预约(平均效用评分 48.34(48.14))更受欢迎,医疗保健专业人员提供的护理被认为非常重要(77.50(64.39))。
DCE 方法可以通过表明患者最重要的属性以及他们在治疗获取和提供方面愿意做出的权衡,帮助资源分配决策。