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来自一家转诊肝胆中心的医源性胆管损伤修复四年报告。

Four-Year Report of Iatrogenic Bile Duct Injury Repair from a Referral Hepatobiliary Center.

作者信息

Zarghami Seyed Yahya, Ghafoury Roya, Fakhar Nasir, Afrashteh Fatemeh, Tasa Davod, Hyder Zeeshan

机构信息

Department of General Surgery, School of Medicine, Firoozgar hospital, Iran University of Medical Sciences, Tehran, Iran.

School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Middle East J Dig Dis. 2024 Jul;16(3):173-177. doi: 10.34172/mejdd.2024.385. Epub 2024 Jul 31.

Abstract

BACKGROUND

Iatrogenic bile duct injury (BDI) is one of the most common complications that challenge surgeons performing laparoscopic cholecystectomy (LC). As the number of LC surgeries increases, a pattern of BDI is emerging, but little is known about this matter. The purpose of this study was to assess the pattern of post-LC BDIs directed in a referral center in Iran.

METHODS

Post-BDI patients referred to a hepatobiliary center were studied. Demographic data, clinical status, diagnostic examinations, referral time, post-referral management, and morbidity were analyzed.

RESULTS

Nine out of 68 patients had Charcot's cholangitis triad featuring right upper quadrant abdominal pain, fever, and icter. Fever, icter, and itching were the most frequent symptoms. Increased bilirubin, leukocytosis, and abnormal liver function test (LFT) were the most common laboratory abnormalities. 30 patients experienced hepatic artery injury. Out of them, six patients experienced hepatectomy due to hepatic ischemia. Two patients were re-admitted and re-operated, and four patients died.

CONCLUSION

Early and correct treatment by a hepatobiliary surgeon experienced in the management of these types of injuries prevents further complications in patients suffering from iatrogenic BDI. Postoperative complications of bile duct repair, such as anastomosis stricture, are possible; thus, patients need long-term and thorough postoperative observation.

摘要

背景

医源性胆管损伤(BDI)是腹腔镜胆囊切除术(LC)外科医生面临的最常见并发症之一。随着LC手术数量的增加,BDI的一种模式正在显现,但对此了解甚少。本研究的目的是评估伊朗一家转诊中心的LC术后BDI模式。

方法

对转诊至肝胆中心的BDI患者进行研究。分析人口统计学数据、临床状况、诊断检查、转诊时间、转诊后管理及发病率。

结果

68例患者中有9例出现夏科氏胆管炎三联征,表现为右上腹腹痛、发热和黄疸。发热、黄疸和瘙痒是最常见的症状。胆红素升高、白细胞增多和肝功能检查(LFT)异常是最常见的实验室异常。30例患者发生肝动脉损伤。其中6例因肝缺血接受肝切除术。2例患者再次入院并再次手术,4例患者死亡。

结论

由在处理这类损伤方面经验丰富的肝胆外科医生进行早期和正确的治疗,可预防医源性BDI患者出现进一步并发症。胆管修复的术后并发症,如吻合口狭窄,是可能发生的;因此,患者需要长期和全面的术后观察。

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