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全身麻醉患者两种Valsalva动作实施技术的比较:一项随机对照研究。

Comparison of two techniques of administering the Valsalva manoeuvre in patients under general anaesthesia: A randomised controlled study.

作者信息

Shah Shagun B, Chaudhary Vineet, Chawla Rajiv, Hariharan Uma, Ghiloria Neha, Dubey Jitendra Kumar

机构信息

Department of Anaesthesia and Critical Care, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, Delhi, India.

Department of Anaesthesia, Sant Parmanand Hospital New Delhi, India.

出版信息

Indian J Anaesth. 2024 Sep;68(9):821-827. doi: 10.4103/ija.ija_1255_23. Epub 2024 Aug 16.

Abstract

BACKGROUND AND AIMS

Surgeons often request a Valsalva manoeuvre (VM) at the end of surgery (head-neck surgery, craniotomy) to check haemostasis and to unmask covert venous bleeders. We aimed to compare an anaesthesia machine-generated objective technique for delivering VM under pressure-control (PC) mode with the traditional subjective technique of delivering VM in manual mode.

METHODS

This randomised controlled study included 60 adult patients randomised to manual (Group M) and controlled ventilation (Group C) groups. Our primary outcome measure was internal jugular vein (IJV) diameter at pre-determined time points (T = baseline, T = VM initiation, T = 20 s after VM initiation, T = immediately after VM release, and T = 1 min, T = 2 min and T = 5 min post-VM release). Secondary outcome measures included mean arterial pressure (MAP), heart rate, time to desired plateau airway pressure, number of patients with bleeders unmasked and surgeon satisfaction. Independent/paired sample -tests were applied. Results are expressed as mean (standard deviation), mean difference (95% confidence interval), dotted box-whisker plots and trendlines. <0.05 is considered statistically significant.

RESULTS

Mean differences in diameter changes in IJV (in centimetres) in the mediolateral and anteroposterior directions between Group C and Group M were -0.136 (-0.227, -0.044) and -0.073 (-0.143, -0.002), respectively. VM in the PC mode produced more significant IJV dilatation ( = 0.004, = 0.044). MAP at T and T was comparable. At T and T, there was a more significant fall in MAP in Group C versus Group M ( = 0.018 and = 0.021, respectively). At T, T and T, MAP was comparable.

CONCLUSION

Performing VM in PC mode is a better technique based on IJV diameter, haemodynamics, bleeder unmasking and surgeon satisfaction.

摘要

背景与目的

外科医生常在手术结束时(头颈手术、开颅手术)要求患者进行瓦尔萨尔瓦动作(VM),以检查止血情况并发现隐匿的静脉出血点。我们旨在比较在压力控制(PC)模式下由麻醉机产生的用于实施VM的客观技术与传统的手动模式下实施VM的主观技术。

方法

这项随机对照研究纳入了60例成年患者,随机分为手动组(M组)和控制通气组(C组)。我们的主要结局指标是在预定时间点(T = 基线、T = VM开始时、T = VM开始后20秒、T = VM释放后即刻、T = VM释放后1分钟、T = 2分钟和T = 5分钟)的颈内静脉(IJV)直径。次要结局指标包括平均动脉压(MAP)、心率、达到所需平台气道压的时间、发现出血点的患者数量以及外科医生的满意度。应用独立/配对样本检验。结果以均值(标准差)、均值差(95%置信区间)、点状箱线图和趋势线表示。P<0.05被认为具有统计学意义。

结果

C组和M组在IJV直径变化(厘米)的内外侧和前后方向上的均值差分别为-0.136(-0.227,-0.044)和-0.073(-0.143,-0.002)。PC模式下的VM使IJV扩张更显著(P = 0.004,P = 0.044)。T1和T2时的MAP相当。在T3和T4时,C组的MAP下降幅度比M组更显著(分别为P = 0.018和P = 0.021)。在T5、T6和T7时,MAP相当。

结论

基于IJV直径、血流动力学、发现出血点情况和外科医生满意度,在PC模式下进行VM是一种更好的技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63d4/11460820/14ec3df25363/IJA-68-821-g001.jpg

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