Lessana A, Romano M, Guérin F, Fouchard J, Adès F, Kara S M, Lefèvre J J, Perron D, Palsky E
Arch Mal Coeur Vaiss. 1985 Dec;78(13):1928-34.
A consecutive series of 130 cases of pure or predominant mitral regurgitation underwent conservative mitral valve surgery between January 1975 and January 1982. The mean age of the patients was 30 +/- 17 years; 25 patients were under 15 years of age. The most common aetiology was rheumatic fever (112/130). Fifty nine patients had associated valvular lesions requiring surgical correction. The patients were divided into 4 groups, according to the surgical technique: Group I: valvular mobilisation (35 cases); Group II: reduction of the amplitude of valvular excursion (48 cases); Group III: mixed valvular mobilisation and reduction of amplitude of excursion (45 cases); Group IV: isolated annuloplasty (2 cases). Hospital mortality was 2.3% (3 patients). Five patients (3.8%) were lost to follow-up. The mean follow-up period was 38 +/- 27 months for the 122 patients followed-up. Seven patients needed reoperation. The long term mortality was 3.1% (4 patients). Four late thromboembolic episodes were observed; they were all transient and regressive in patients with atrial fibrillation. The 7 year actuarial survival rate for the whole series, including hospital mortality, was 92% (1.0 +/- 0.5 patients/year). It was 93.7 +/- 4.9% at 7 years for isolated mitral valvuloplasty and 89.9% +/- 5.6% at 5 years for combined mitro-tricuspid procedures. The actuarial percentage of patients without thromboembolic complications was 91.2% at 7 years with a thromboembolic risk of 1.0 +/- 0.5% patients/year. Eighty eight per cent of patients were not reoperated at 7 years and the reoperation rate was 1.7 +/- 0.7% patients/year.(ABSTRACT TRUNCATED AT 250 WORDS)
1975年1月至1982年1月期间,连续130例单纯或主要为二尖瓣反流的患者接受了二尖瓣保守手术。患者的平均年龄为30±17岁;25例患者年龄在15岁以下。最常见的病因是风湿热(112/130)。59例患者伴有需要手术矫正的瓣膜病变。根据手术技术,患者被分为4组:第一组:瓣膜松动术(35例);第二组:减少瓣膜活动幅度(48例);第三组:瓣膜松动术与减少活动幅度相结合(45例);第四组:单纯瓣环成形术(2例)。医院死亡率为2.3%(3例患者)。5例患者(3.8%)失访。122例接受随访患者的平均随访期为38±27个月。7例患者需要再次手术。长期死亡率为3.1%(4例患者)。观察到4例晚期血栓栓塞事件;在房颤患者中,这些事件均为短暂性且逐渐消退。整个系列(包括医院死亡率)的7年精算生存率为92%(1.0±0.5例患者/年)。单纯二尖瓣成形术7年时为93.7±4.9%,二尖瓣-三尖瓣联合手术5年时为89.9%±5.6%。7年时无血栓栓塞并发症患者的精算百分比为91.2%,血栓栓塞风险为1.0±0.5%患者/年。88%的患者7年时未再次手术,再次手术率为1.7±0.7%患者/年。(摘要截短于250字)