Talwar Sidhant, Maldar Shadab, Mudda Abhishek, J Pinto Christopher, Julovich Alicia
Department of Internal Medicine, Vijayanagar Institute of Medical Sciences, Ballari, Karnataka, India.
Department of Internal Medicine, Karnataka Institute of Medical Sciences, Hubballi, Karnataka, India.
Radiol Case Rep. 2024 Sep 24;19(12):6241-6245. doi: 10.1016/j.radcr.2024.08.138. eCollection 2024 Dec.
Dyke-Davidoff-Masson syndrome is a rare neurological condition characterized by intractable seizures, cerebral hemiatrophy with contralateral hemiparesis. Our patient, a 38-year-old female, presented following a left focal seizure with secondary generalization. She had a history of epilepsy, associated with left-sided hemiparesis, beginning at the age of 7. Physical examination showed increased left-sided tone and brisk reflexes, with an extensor plantar reflex on the left. The MRI brain showed features suggestive of Dyke-Davidoff-Masson syndrome: right-sided cortical atrophy, calvarial thickening and dilated frontal sinus. Additional MRI findings were of right cerebral peduncle atrophy and left cerebellar atrophy. This case report intends to emphasize the importance of Dyke-Davidoff-Masson syndrome as an unusual cause of seizures in an adult complicated by poor social determinants of health, leading to its delayed diagnosis.
戴克-戴维多夫-马森综合征是一种罕见的神经系统疾病，其特征为顽固性癫痫发作、伴有对侧偏瘫的大脑半球萎缩。我们的患者是一名38岁女性，因左侧局灶性癫痫发作继发全身发作前来就诊。她有癫痫病史，自7岁起伴有左侧偏瘫。体格检查显示左侧肌张力增高、反射亢进，左侧巴宾斯基征阳性。脑部磁共振成像（MRI）显示有提示戴克-戴维多夫-马森综合征的特征：右侧皮质萎缩、颅骨增厚和额窦扩张。MRI的其他表现为右侧大脑脚萎缩和左侧小脑萎缩。本病例报告旨在强调戴克-戴维多夫-马森综合征作为成人癫痫发作的一种不寻常病因的重要性，该病因因不良的健康社会决定因素而导致诊断延迟。
