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Exploring the role of EZH2 modulation in shaping the tumor microenvironment.

作者信息

Fischetti Irene, De Luca Michele, Jachetti Elena

机构信息

Molecular Immunology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.

Integrated Biology of Rare Tumors Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.

出版信息

Epigenomics. 2024;16(19-20):1265-1268. doi: 10.1080/17501911.2024.2410693. Epub 2024 Oct 10.

DOI:10.1080/17501911.2024.2410693
PMID:39387445
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11534139/
Abstract
摘要

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Epigenomics. 2024 Mar 26;16(9):653-70. doi: 10.2217/epi-2023-0374.
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EZH2-mediated development of therapeutic resistance in cancer.EZH2 介导的癌症治疗抵抗的发生。
Cancer Lett. 2024 Apr 1;586:216706. doi: 10.1016/j.canlet.2024.216706. Epub 2024 Feb 7.
3
Regulation of EZH2 protein stability: new mechanisms, roles in tumorigenesis, and roads to the clinic.EZH2 蛋白稳定性的调控：新机制、在肿瘤发生中的作用和走向临床。
EBioMedicine. 2024 Feb;100:104972. doi: 10.1016/j.ebiom.2024.104972. Epub 2024 Jan 19.
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Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer.EZH2 对 CCL2 的调控影响乳腺癌中肿瘤相关巨噬细胞的极化和浸润。
Cell Death Dis. 2022 Aug 29;13(8):748. doi: 10.1038/s41419-022-05169-x.
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The Role of Polycomb Proteins in Cell Lineage Commitment and Embryonic Development.多梳蛋白在细胞谱系定向分化和胚胎发育中的作用
Epigenomes. 2022 Aug 12;6(3):23. doi: 10.3390/epigenomes6030023.
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Front Immunol. 2022 Apr 1;13:857808. doi: 10.3389/fimmu.2022.857808. eCollection 2022.
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Biochim Biophys Acta Rev Cancer. 2022 Mar;1877(2):188700. doi: 10.1016/j.bbcan.2022.188700. Epub 2022 Feb 22.
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