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本文引用的文献

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Microfragmented adipose tissue in the treatment of a full-thickness supraspinatus tear: a case report.微片段化脂肪组织治疗全层冈上肌撕裂:一例报告
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2
Complete Rupture of Common Extensor Origin of Elbow: A Rare Case Report, Management, and Outcome.肘部伸肌总起点完全断裂:一例罕见病例报告、治疗及结果
J Orthop Case Rep. 2023 Mar;13(3):23-27. doi: 10.13107/jocr.2023.v13.i03.3570.
3
A Positive Correlation between Steroid Injections and Cuff Tendon Tears: A Cohort Study Using a Clinical Database.类固醇注射与肩袖肌腱撕裂的正相关性:一项基于临床数据库的队列研究。
Int J Environ Res Public Health. 2022 Apr 8;19(8):4520. doi: 10.3390/ijerph19084520.
4
Effectiveness of Platelet-Rich Plasma for Lateral Epicondylitis: A Systematic Review and Meta-analysis Based on Achievement of Minimal Clinically Important Difference.富血小板血浆治疗外侧上髁炎的有效性:基于达到最小临床重要差异的系统评价和荟萃分析
Orthop J Sports Med. 2022 Apr 8;10(4):23259671221086920. doi: 10.1177/23259671221086920. eCollection 2022 Apr.
5
The Crosstalk Between Adipose-Derived Stem or Stromal Cells (ASC) and Cancer Cells and ASC-Mediated Effects on Cancer Formation and Progression-ASCs: Safety Hazard or Harmless Source of Tropism?脂肪来源的干细胞或基质细胞 (ASC) 与癌细胞的串扰及 ASC 对癌症发生和进展的影响——ASC:是安全隐患还是无偏向性来源?
Stem Cells Transl Med. 2022 Apr 29;11(4):394-406. doi: 10.1093/stcltm/szac002.
6
Trends in Corticosteroid Injections for Treatment of Lateral Epicondylitis: An Analysis of 80,169 Patients.治疗外侧肱骨上髁炎的皮质类固醇注射趋势:对 80169 名患者的分析。
J Am Acad Orthop Surg Glob Res Rev. 2021 Sep 10;5(9):e21.00186. doi: 10.5435/JAAOSGlobal-D-21-00186.
7
Achilles Tendinopathy: Evaluation, Rehabilitation, and Prevention.跟腱病:评估、康复和预防。
Curr Sports Med Rep. 2021 Jun 1;20(6):327-334. doi: 10.1249/JSR.0000000000000855.
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Diagnostic accuracy of examination tests for lateral elbow tendinopathy (LET) - A systematic review.外侧肘肌腱病(LET)检查测试的诊断准确性——一项系统评价。
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9
Promising improvement of chronic lateral elbow tendinopathy by using adipose derived mesenchymal stromal cells: a pilot study.使用脂肪源性间充质基质细胞有望改善慢性外侧肘肌腱病:一项试点研究。
J Exp Orthop. 2021 Jan 26;8(1):6. doi: 10.1186/s40634-020-00320-z.
10
Adipose Tissue Fibrosis: Mechanisms, Models, and Importance.脂肪组织纤维化:机制、模型与重要性。
Int J Mol Sci. 2020 Aug 21;21(17):6030. doi: 10.3390/ijms21176030.

经皮微小脂肪移植后全层伸肌腱撕裂的再生

Regeneration of full thickness common extensor tendon tear after percutaneous microfragmented adipose graft.

作者信息

Siddiqui Imran J, Ritner Alyssa, Mahadevan Sanjay, Dineen Kyle J, Desronvilles Roosevelt

机构信息

Regenerative Orthopedics and Sports Medicine, Rockville Pike #300, Rockville, MD 20852, USA.

出版信息

Regen Med. 2024 Sep-Oct;19(9-10):463-472. doi: 10.1080/17460751.2024.2393555. Epub 2024 Oct 10.

DOI:10.1080/17460751.2024.2393555
PMID:39387455
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11487942/
Abstract

Tennis elbow, also commonly known as lateral epicondylitis or common extensor tendinosis, is a common musculoskeletal injury in the adult population. Currently, the standard treatment regimen prescribed for this injury involves a combination of rest, physical therapy, bracing and anti-inflammatory medications. If refractory to these conservative measures, platelet-rich plasma has been shown effective. However, in the case of full thickness tears, surgery has remained the only treatment option until now. We present a case report of a 56-year-old man with a diagnosis of a left large full thickness tear and rupture with retraction of his common extensor tendon (CET) following a corticosteroid injection. The patient was treated with microfragmented adipose transfer. He was re-evaluated around 7 weeks and again at 15 weeks post-treatment and demonstrated ultrasound evidence of complete bridging and remodeling of his prior full thickness CET tear and resolution of retraction. This case presents a promising option for patients with full thickness CET tears who would like to refrain from or are unable to have surgery. Further research and possible randomized controlled trials are needed to further assess the full efficacy of microfragmented adipose transfer in the treatment of full thickness CET tears.

摘要

网球肘,也通常被称为外侧上髁炎或常见伸肌肌腱病,是成年人群中常见的肌肉骨骼损伤。目前,针对这种损伤规定的标准治疗方案包括休息、物理治疗、支具固定和抗炎药物联合使用。如果对这些保守措施无效,已证明富血小板血浆是有效的。然而,对于全层撕裂的情况,到目前为止手术仍然是唯一的治疗选择。我们报告一例56岁男性病例,该患者在接受皮质类固醇注射后,诊断为左上肢常见伸肌肌腱(CET)全层撕裂并伴有回缩和断裂。该患者接受了微片段脂肪移植治疗。在治疗后约7周和15周时对他进行了再次评估,超声检查显示其先前的CET全层撕裂已完全桥接和重塑,回缩也已消失。对于那些希望避免手术或无法进行手术的CET全层撕裂患者,该病例提供了一个有前景的选择。需要进一步的研究以及可能的随机对照试验来进一步评估微片段脂肪移植治疗CET全层撕裂的全部疗效。