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雌激素和孕酮对猫子宫中糖原及其代谢相关酶的影响。

The effects of estrogen and progesterone on glycogen and the enzymes involved in its metabolism in the cat uterus.

作者信息

Jaffe R C, Stevens D M, Verhage H G

出版信息

Steroids. 1985 May;45(5):453-62. doi: 10.1016/0039-128x(85)90010-8.

DOI:10.1016/0039-128x(85)90010-8
PMID:3938883
Abstract

In the endometrium of the spay cat, estradiol treatment causes a drastic reduction in glycogen content. The initiation of simultaneous progesterone treatment causes a replenishment of glycogen with the levels surpassing those observed in the spayed animal. The effect of the hormones on glycogen synthetase I follows the same pattern as the changes in glycogen content, while the effect on phosphorylase a is the mirror image. The total content of glycogen synthetase and phosphorylase do not show appreciable changes with the same hormone treatment. The possible reproductive role of these changes in glycogen content are discussed.

摘要

在绝育猫的子宫内膜中,雌二醇治疗会导致糖原含量急剧下降。同时开始孕酮治疗会使糖原补充,其水平超过绝育动物中观察到的水平。激素对糖原合成酶I的作用与糖原含量变化遵循相同模式,而对磷酸化酶a的作用则相反。糖原合成酶和磷酸化酶的总含量在相同激素治疗下没有明显变化。本文讨论了这些糖原含量变化可能的生殖作用。

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