Edminster S C, Bayer M J
J Emerg Med. 1985;3(5):365-70. doi: 10.1016/0736-4679(85)90321-x.
Gasoline is a readily obtainable intoxicant that unfortunately lends itself to habitual abuse by sniffing, a practice found particularly among children and adolescents. The concerted effects of the multiple hydrocarbon and other constituents of gasoline result in a predictable acute toxic syndrome. Organoleads, primarily tetraethyl lead (TEL), cause a separate toxicologic symptom-sign complex that overlaps with the initial acute toxic syndrome. The different clinical symptomatology, effects on hemoglobin synthesis, and response to chelation therapy are all in keeping with the view that organolead poisoning is a separate and distinct toxicologic entity from that of classical elemental lead poisoning or "plumbism".
汽油是一种容易获取的致醉物，不幸的是，它容易被人习惯性地通过嗅吸来滥用，这种行为在儿童和青少年中尤为常见。汽油中多种碳氢化合物和其他成分的协同作用会导致一种可预测的急性中毒综合征。有机铅，主要是四乙基铅（TEL），会引发一种单独的毒理学症状体征复合体，与最初的急性中毒综合征相互重叠。不同的临床症状、对血红蛋白合成的影响以及对螯合疗法的反应，都与有机铅中毒是一种与经典的元素铅中毒或“铅中毒”不同的独立毒理学实体这一观点相符。
