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缺铁性贫血时红细胞超氧化物歧化酶增加。

Red cell superoxide dismutase is increased in iron deficiency anemia.

作者信息

Jansson L T, Perkkiö M V, Willis W T, Refino C J, Dallman P R

出版信息

Acta Haematol. 1985;74(4):218-21. doi: 10.1159/000206222.

DOI:10.1159/000206222
PMID:3939064
Abstract

Red blood cells (RBC) from iron-deficient rats were found to generate more malonyldialdehyde after in vitro incubation with H2O2 than RBC from control rats (p less than 0.001). The iron-deficient RBC, however, had a higher content of superoxide dismutase (SOD) than control RBC (p less than 0.02). This finding suggests an increased formation of SOD compensatory to an increased oxidant stress.

摘要

缺铁大鼠的红细胞在与过氧化氢进行体外孵育后,被发现比对照大鼠的红细胞产生更多的丙二醛(p小于0.001)。然而,缺铁红细胞的超氧化物歧化酶(SOD)含量高于对照红细胞(p小于0.02)。这一发现表明,SOD的形成增加是对氧化应激增加的一种代偿。

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1
Red cell superoxide dismutase is increased in iron deficiency anemia.缺铁性贫血时红细胞超氧化物歧化酶增加。
Acta Haematol. 1985;74(4):218-21. doi: 10.1159/000206222.
2
Red cell lipid peroxidation and antioxidant enzymes in iron deficiency.缺铁状态下的红细胞脂质过氧化与抗氧化酶
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Note to the paper 'Red cell superoxide dismutase is increased in iron deficiency anemia'.致论文《缺铁性贫血时红细胞超氧化物歧化酶增加》的注释
Acta Haematol. 1986;76(2-3):181. doi: 10.1159/000206050.
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[Superoxide dismutase activity in the blood of children with iron deficiency anemia].[缺铁性贫血患儿血液中的超氧化物歧化酶活性]
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Evidence of peroxidative damage to the erythrocyte membrane in iron deficiency.缺铁时红细胞膜过氧化损伤的证据。
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Automated measurement of red blood cell microcytosis and hypochromia in iron deficiency and beta-thalassemia trait.缺铁性贫血和β地中海贫血特征中红细胞小红细胞症和低色素症的自动测量
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Red cell membrane stiffness in iron deficiency.缺铁状态下的红细胞膜硬度
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Copper activation of superoxide dismutase in rat erythrocytes.铜对大鼠红细胞中超氧化物歧化酶的激活作用。
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[Effect of iron therapy on vitamin B 6 concentration in children with hypochromic anemia].[铁剂治疗对低色素性贫血患儿维生素B6浓度的影响]
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