缺铁性贫血时红细胞超氧化物歧化酶增加。
Red cell superoxide dismutase is increased in iron deficiency anemia.
作者信息
Jansson L T, Perkkiö M V, Willis W T, Refino C J, Dallman P R
出版信息
Acta Haematol. 1985;74(4):218-21. doi: 10.1159/000206222.
PMID:3939064
Abstract
Red blood cells (RBC) from iron-deficient rats were found to generate more malonyldialdehyde after in vitro incubation with H2O2 than RBC from control rats (p less than 0.001). The iron-deficient RBC, however, had a higher content of superoxide dismutase (SOD) than control RBC (p less than 0.02). This finding suggests an increased formation of SOD compensatory to an increased oxidant stress.
摘要
缺铁大鼠的红细胞在与过氧化氢进行体外孵育后，被发现比对照大鼠的红细胞产生更多的丙二醛（p小于0.001）。然而，缺铁红细胞的超氧化物歧化酶（SOD）含量高于对照红细胞（p小于0.02）。这一发现表明，SOD的形成增加是对氧化应激增加的一种代偿。
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