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腺样体扁桃体切除术患儿围手术期抗生素治疗的疗效。

The efficacy of perioperative antibiotic therapy in adenotonsillectomy children.

机构信息

Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, No.355, Luding Road, Shanghai, 200062, People's Republic of China.

出版信息

Eur Arch Otorhinolaryngol. 2024 Jan;281(1):267-272. doi: 10.1007/s00405-023-08244-x. Epub 2023 Sep 22.

Abstract

PURPOSE

To evaluate the role of perioperative antibiotics use in children after adenotonsillectomy.

METHODS

SPSS 27.0 was used for statistical analysis. Two independent samples mean T test was used to evaluate the throat pain scores consecutive 3 days after the surgery, the time to resume to normal diet, and the wound healing time. Logistic regression analysis was used to evaluate the independent risk factors of the two groups. The generalized estimation model was used to evaluate the correlation between age and postoperative pain scores, and the relationship between different tonsillar bed gradings and postoperative pain scores.

RESULTS

The pain scores were 5.83 ± 1.879, 5.20 ± 1.933, and 4.02 ± 1.936 in the observation group; and 6.83 ± 1.892, 6.17 ± 2.001, and 5.29 ± 2.068 in the control group on days 1-3 after surgery, respectively. The time of pain disappearance was 6.24 ± 2.121 days in the observation group and 7.73 ± 2.210 days in the control group. The wound repair time was 18.66 ± 2.200 days in the observation group and 18.70 ± 2.468 days in the control group. Logistic regression analysis showed that fever was an independent risk factor for the two groups and was negatively correlated (B =  - 1.237, P < 0.001, OR = 0.290). Generalized estimation model showed that there was a positive correlation between age and pain scores (P < 0.001), and with the increasing grading of tonsillar bed, the higher the pain scores was (P < 0.001).

CONCLUSIONS

Perioperative use of antibiotics in children with adenotonsillectomy can effectively reduce postoperative fever, throat pain symptoms, and shorten the pain time. With the increasing of tonsillar bed grading, perioperative antibiotic therapy was more necessary.

摘要

目的

评估围手术期使用抗生素对腺样体扁桃体切除术后儿童的作用。

方法

采用 SPSS27.0 进行统计学分析。采用两独立样本均数 T 检验评估术后连续 3 天的咽痛评分、恢复正常饮食时间和伤口愈合时间。采用 Logistic 回归分析评估两组的独立危险因素。采用广义估计模型评估年龄与术后疼痛评分的相关性,以及不同扁桃体床分级与术后疼痛评分的关系。

结果

观察组术后第 1-3 天的疼痛评分分别为 5.83±1.879、5.20±1.933 和 4.02±1.936,对照组分别为 6.83±1.892、6.17±2.001 和 5.29±2.068。观察组疼痛消失时间为 6.24±2.121 天,对照组为 7.73±2.210 天。观察组伤口修复时间为 18.66±2.200 天,对照组为 18.70±2.468 天。Logistic 回归分析显示,发热是两组的独立危险因素,呈负相关(B=−1.237,P<0.001,OR=0.290)。广义估计模型显示,年龄与疼痛评分呈正相关(P<0.001),且随着扁桃体床分级的增加,疼痛评分越高(P<0.001)。

结论

腺样体扁桃体切除术中围手术期使用抗生素可有效减轻术后发热、咽痛症状,缩短疼痛时间。随着扁桃体床分级的增加,围手术期抗生素治疗更为必要。

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